Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | TACR2 | P21452 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TST | Q16762 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1313200 | 1.00 | HTR2A (0.60) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1009348 | 1.00 | HTR2A (0.60) | HTR2AESR1ADRA2AADORA3TACR2 | |
| Hydrochloric Acid SCHEMBL11737570 | 0.98 | HTR2A (0.58) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL19174795 | 0.98 | HTR2A (0.57) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL29342921 | 0.92 | HTR2A (0.50) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL11686889 | 0.92 | HTR2A (0.50) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL29342569 | 0.92 | HTR2A (0.50) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL30469503 | 0.86 | HTR2A (0.62) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL6861225 | 0.86 | HTR2A (0.62) | HTR2AESR1ADRA2AADORA3TACR2 | |
| Hydrochloric Acid SCHEMBL27998571 | 0.86 | HTR2A (0.62) | HTR2AESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148530-A1 | Method for the treatment or prevention of virus infection using polybiguanide-based compounds | NOVAFLUX BIOSCIENCES, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20110275673-A1 | INHIBITORS OF SPHINGOSINE KINASE 1 | GENZYME CORPORATION | 2011-11-10 | — | — | US | disclosed |
| US-20110275673-A1 | INHIBITORS OF SPHINGOSINE KINASE 1 | GENZYME CORPORATION | 2011-11-10 | — | — | US | disclosed |
| US-7772284-B2 | Method for the treatment or prevention of virus infection using polybiguanide-based compounds | NOVAFLUX INC. | 2010-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275673-A1 | INHIBITORS OF SPHINGOSINE KINASE 1 | SPHK1, SPHK2, S1PR1 | HTR2A 4137/4885ESR1 4317/4885ADRA2A 2758/4885 |
| US-20120148530-A1 | Method for the treatment or prevention of virus infection using polybiguanide-based compounds | SAMHD1, TK1, SORD | HTR2A 4878/4885ESR1 3740/4885ADRA2A 4883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.