Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639716 | 0.93 | HTR2A (0.66) | HTR2ATAAR1CA2ALDH1A1HSD17B10 | |
| SCHEMBL6182941 | 0.88 | TAAR1 (0.54) | HTR2ATAAR1CA2ALDH1A1HPGD | |
| SCHEMBL10977710 | 0.84 | CA2 (0.47) | HTR2ACA2SMN1; SMN2CA1ALDH1A1 | |
| SCHEMBL27718310 | 0.82 | CA2 (0.46) | HTR2ACA2SMN1; SMN2CA1ALDH1A1 | |
| SCHEMBL30368395 | 0.82 | CA2 (0.46) | HTR2ACA2SMN1; SMN2CA1ALDH1A1 | |
| SCHEMBL23522328 | 0.81 | TAAR1 (0.47) | HTR2ATAAR1CA2ESR1 | |
| SCHEMBL11686889 | 0.80 | HTR2A (0.50) | HTR2ACA2SMN1; SMN2CA1ALDH1A1 | |
| SCHEMBL29342569 | 0.80 | HTR2A (0.50) | HTR2ACA2SMN1; SMN2CA1ALDH1A1 | |
| SCHEMBL29342921 | 0.80 | HTR2A (0.50) | HTR2ACA2SMN1; SMN2CA1ALDH1A1 | |
| SCHEMBL8090819 | 0.79 | UCHL3 (0.56) | HTR2ACA2SMN1; SMN2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998033496-A1 | SULPHONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |