Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637549 | 0.88 | HTR2A (0.56) | TAAR1HTR2ACA2ESR1KDM4E | |
| SCHEMBL7639716 | 0.85 | HTR2A (0.66) | TAAR1HTR2ACA2LPLLIPG | |
| SCHEMBL20036657 | 0.83 | LPL (0.43) | CA2LPLLIPGACACBESR1 | |
| SCHEMBL3006604 | 0.82 | TAAR1 (0.75) | TAAR1HTR2AESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL6564727 | 0.79 | TAAR1 (0.71) | TAAR1HTR2AESR1ESR2KDM4E | |
| SCHEMBL10130853 | 0.79 | LPL (0.45) | CA2LPLLIPGACACBESR1 | |
| SCHEMBL14873127 | 0.79 | HTR2A (0.46) | TAAR1HTR2ACA2LPLLIPG | |
| SCHEMBL4796978 | 0.78 | ADRB2 (0.48) | TAAR1HTR2ACA2LPLLIPG | |
| SCHEMBL7043601 | 0.78 | ADRB2 (0.48) | TAAR1HTR2ACA2LPLLIPG | |
| Hydrochloric Acid SCHEMBL27512774 | 0.78 | TAAR1 (0.58) | TAAR1CA2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529038-A1 | BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECEPTOR AGONIST ACTIVITY | Novartis AG (CH) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004016601-A1 | BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECEPTOR AGONIST ACTIVITY | NOVARTIS AG (CH) | 2004-02-26 | — | — | WO | disclosed |