SCHEMBL7640405

SCHEMBL7640405

C=C(C)C(=O)O[Si](C)(C)OC(=O)COCC

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
ALDH1A1 P00352 3/20 0.34
TSHR P16473 4/20 0.33
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7638438 0.81 ALDH1A1 (0.41) THRBALDH1A1TSHR
SCHEMBL7641990 0.81 THRB (0.42) THRBALDH1A1TSHR
SCHEMBL27878775 0.78 ALDH1A1 (0.33) ALDH1A1TSHRMGAMGAASI
SCHEMBL3446620 0.78 ALDH1A1 (0.52) THRBALDH1A1TSHR
SCHEMBL27495304 0.77 THRB (0.52) THRBALDH1A1TSHRMGAMGAA
SCHEMBL4906698 0.75 THRB (0.44) THRBALDH1A1TSHRMGAMGAA
SCHEMBL3400820 0.74 ALDH1A1 (0.48) THRBALDH1A1TSHR
SCHEMBL17589284 0.72 ALDH1A1 (0.46) THRBALDH1A1TSHR
SCHEMBL5711152 0.71 ALDH1A1 (0.41) THRBALDH1A1TSHR
SCHEMBL3295003 0.71 ALDH1A1 (0.41) THRBALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399212-B1 COATINGS WITH ORGANOSILICON COMPOUNDS AND SOLUTION OF SILICOFLUORIC ACID AND SILICON DIOXIDE NIPPON SHEET GLASS CO., LTD. (JP) 2002-06-04 US disclosed
EP-1094090-A2 Silicon dioxide-coated polyolefin resin and process for its production NIPPON SHEET GLASS CO. LTD. (JP) 2001-04-25 EP disclosed