SCHEMBL4906698

SCHEMBL4906698

C=C(C)C(=O)O[Si](C)(C)OCC

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
ALDH1A1 P00352 4/20 0.41
TSHR P16473 4/20 0.38
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1781555 0.83 THRB (0.44) THRBALDH1A1TSHRLMNAHSD17B10
SCHEMBL3446620 0.81 ALDH1A1 (0.52) THRBALDH1A1TSHRHSD17B10
SCHEMBL1419614 0.80 THRB (0.45) THRBALDH1A1TSHRLMNAHSD17B10
SCHEMBL25389391 0.78 TDP1 (0.52) THRBALDH1A1TSHRLMNAHSD17B10
SCHEMBL27550157 0.78 ALDH1A1 (0.41) THRBALDH1A1TSHR
SCHEMBL7642768 0.78 ALDH1A1 (0.41) THRBALDH1A1TSHR
SCHEMBL15514061 0.77 THRB (0.42) THRBALDH1A1TSHRLMNAHSD17B10
SCHEMBL3400820 0.77 ALDH1A1 (0.48) THRBALDH1A1TSHRHSD17B10
SCHEMBL5702010 0.76 TSHR (0.38) THRBALDH1A1TSHR
SCHEMBL7640405 0.75 THRB (0.46) THRBALDH1A1TSHRMGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112789065-A Medical device 微仙美国有限公司 2021-05-11 CN disclosed
US-20080038679-A1 DEVELOPING AGENT AND MANUFACTURING METHOD THEREOF KABUSHIKI KAISHA TOSHIBA (JP) 2008-02-14 US disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 THRB 4533/4885ALDH1A1 402/4885TSHR 4650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.