Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638924 | 0.86 | LMNA (0.42) | LMNATHRBF2PRSS1PRSS2 | |
| SCHEMBL6257714 | 0.85 | THRB (0.31) | LMNATHRB | |
| SCHEMBL6256217 | 0.85 | THRB (0.31) | LMNATHRB | |
| SCHEMBL7638933 | 0.84 | LMNA (0.33) | LMNATHRBF2PRSS1PRSS2 | |
| SCHEMBL346173 | 0.83 | LMNA (0.44) | LMNATHRBF2PRSS1PRSS2 | |
| SCHEMBL6236464 | 0.83 | LMNA (0.44) | LMNATHRBF2PRSS1PRSS2 | |
| SCHEMBL623448 | 0.83 | LMNA (0.44) | LMNATHRBF2PRSS1PRSS2 | |
| SCHEMBL1800782 | 0.83 | LMNA (0.44) | LMNATHRBF2PRSS1PRSS2 | |
| SCHEMBL6443127 | 0.83 | LMNA (0.44) | LMNATHRBF2PRSS1PRSS2 | |
| SCHEMBL50596 | 0.83 | LMNA (0.44) | LMNATHRBF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468502-B1 | PARAMAGNETIC MACROMOLECULES WITH HIGHER PROTON RELAXIVITY; LOWER DOSAGE AND INCREASED SIGNAL INTENSITY; DETECTING VASCULAR DISEASES; DIFFERENTIATING TISSUE BLOOD SUPPLY LEVELS; DISTINGUISHING MYOCARDIAL INFARCTION FROM ISCHEMIA | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |