Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10888499 | 0.88 | APOBEC3G (0.44) | PDCD1CD274HPGDLMNAGAA | |
| Acetic Acid SCHEMBL27549725 | 0.87 | PTPN1 (0.41) | LMNAALDH1A1POLQCYP1A2TSHR | |
| Acetic Acid SCHEMBL27587476 | 0.80 | NPC1 (0.50) | ALDH1A1CYP1A2SMN1; SMN2MAOAMAOB | |
| SCHEMBL2221854 | 0.77 | ALDH1A1 (0.50) | LMNAL3MBTL1ALDH1A1CYP1A2SMN1; SMN2 | |
| Acetic Acid SCHEMBL28614085 | 0.76 | HPGD (0.39) | HPGDLMNAGAAALDH1A1CYP1A2 | |
| SCHEMBL7159107 | 0.74 | CYP4F2 (0.39) | PDCD1CD274HPGDLMNAGAA | |
| Salicyl Alcohol SCHEMBL4149772 | 0.74 | AKR1B1 (0.59) | PDCD1CD274HPGDLMNAGAA | |
| Acetic Acid SCHEMBL5037208 | 0.74 | HPGD (0.50) | PDCD1CD274HPGDLMNAGAA | |
| Carbamic Acid SCHEMBL31333088 | 0.73 | MAPT (0.42) | PDCD1CD274HPGDLMNAGAA | |
| SCHEMBL1759386 | 0.73 | KDM4E (0.43) | HPGDLMNAL3MBTL1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465407-B2 | LAUNDRY COMPRISING OF A THIN LAYER CONTAINING AT LEAST ONE OF DETERGENTS FOR CLOTHES, FIBER SOFTENERS, AND BLEACHES AND A SUPPORT FOR THE THIN LAYER; PACKAGED PRODUCT; NONLEAKING, EASILY DISPENSED | KAO CORPORATION (JP) | 2002-10-15 | — | — | US | disclosed |