Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372186 | 0.89 | AOC3 (0.47) | LMNACES2CES1MAPK1AOC3 | |
| SCHEMBL7434679 | 0.89 | AOC3 (0.47) | LMNACES2CES1MAPK1AOC3 | |
| SCHEMBL23172374 | 0.89 | AOC3 (0.47) | LMNACES2CES1MAPK1AOC3 | |
| Alcohol SCHEMBL10526338 | 0.83 | LMNA (0.48) | LMNAAOC3ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL14632149 | 0.77 | AOC3 (0.55) | HPGDLMNACES2CES1MAPK1 | |
| Acetic Acid SCHEMBL11490434 | 0.76 | SMN1; SMN2 (0.43) | LMNAHTTALDH1A1CYP3A4CYP2D6 | |
| Diphenylmethanol SCHEMBL28093890 | 0.75 | LMNA (0.54) | HPGDLMNACES2CES1MAPK1 | |
| Acetic Acid SCHEMBL18759652 | 0.74 | LMNA (0.56) | HPGDLMNACES2CES1MAPK1 | |
| SCHEMBL60356 | 0.74 | AOC3 (0.57) | HPGDLMNACES2CES1MAPK1 | |
| SCHEMBL9683893 | 0.74 | AOC3 (0.57) | HPGDLMNACES2CES1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443174-B | Cosmetic composition containing low molecular weight amorphous polylactic acid resin | 自然工作有限责任公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115443174-A | Cosmetic composition containing low molecular weight amorphous polylactic acid resin | 自然工作有限责任公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-113950465-A | Fragrance compound of sandalwood type | 西姆莱斯股份公司 | 2022-01-18 | — | — | CN | disclosed |
| CN-108367088-B | Composition and delivery system and filling for spraying two or more compositions | 约翰逊父子公司 | 2021-07-06 | — | — | CN | disclosed |
| US-6465407-B2 | LAUNDRY COMPRISING OF A THIN LAYER CONTAINING AT LEAST ONE OF DETERGENTS FOR CLOTHES, FIBER SOFTENERS, AND BLEACHES AND A SUPPORT FOR THE THIN LAYER; PACKAGED PRODUCT; NONLEAKING, EASILY DISPENSED | KAO CORPORATION (JP) | 2002-10-15 | — | — | US | disclosed |
| US-4396523-A | SCENTS IN COSMETICS AND CLEANING COMPOUNDS | HAARMANN & REIMER GMBH (DE) | 1983-08-02 | — | — | US | disclosed |
| US-4292210-A | PERFUMES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-29 | — | — | US | disclosed |