SCHEMBL764062

SCHEMBL764062

NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSL P07711 3/20 0.68
TACR1 P25103 2/20 0.65
CTSB P07858 2/20 0.64
CTSS P25774 2/20 0.64
CTSK P43235 2/20 0.64
ALDH1A1 P00352 1/20 0.62
ALOX15 P16050 1/20 0.62
CTRB1 P17538 2/20 0.61
ITGB3 P05106 4/20 0.58
ITGA2B P08514 4/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6387189 1.00 CTSL (0.68) CTSLTACR1CTSBCTSSCTSK
SCHEMBL10250520 1.00 CTSL (0.68) CTSLTACR1CTSBCTSSCTSK
SCHEMBL6378208 0.91 CTSL (0.72) CTSLTACR1CTSBCTSSCTSK
SCHEMBL1663171 0.90 CTSL (0.71) CTSLTACR1CTSBCTSSCTSK
SCHEMBL1661924 0.90 CTSL (0.71) CTSLTACR1CTSBCTSSCTSK
SCHEMBL7285798 0.88 ALDH1A1 (0.74) CTSLTACR1CTSBCTSSCTSK
SCHEMBL9848836 0.88 CTSL (0.58) CTSLTACR1CTSBCTSSCTSK
SCHEMBL8785257 0.88 ALDH1A1 (0.74) CTSLTACR1CTSBCTSSCTSK
SCHEMBL8785267 0.88 ALDH1A1 (0.74) CTSLTACR1CTSBCTSSCTSK
SCHEMBL31705215 0.88 CAPN1 (0.74) CTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0561303-A2 Conjugates of phenylalanine-glycine with antitumor substances KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1993-09-22 EP claimed
EP-0071926-B1 NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-10-08 EP claimed
EP-0071926-A1 New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-02-16 EP claimed
JP-5255387-A None JP disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
WO-2023017794-A1 POLYALKYLENE-OXIDE-CONTAINING COMPOUND 株式会社日本触媒 2023-02-16 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
EP-0410411-A2 Novel peptidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1991-01-30 EP disclosed
EP-0376012-A2 Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1990-07-04 EP disclosed
EP-0094815-B1 OLIGOPEPTIDE PRODRUGS SMITHKLINE BECKMAN CORPORATION (US) 1989-01-11 EP disclosed
EP-0071926-B1 NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-10-08 EP disclosed
US-4479942-A Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-10-30 US disclosed
US-4454065-A INCREASE CELL MEMBRANE PERMEABILITY SMITHKLINE BECKMAN CORPORATION (US) 1984-06-12 US disclosed
EP-0071926-A1 New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-02-16 EP disclosed
US-4242507-A Sulfonic acid esters FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 US disclosed
US-4172130-A α-AMINOACYL CONTAINING NEW PEPTIDES WITH GASTRIN EFFECTS AND A PROCESS FOR THE PREPARATION THEREOF RICHTER GEDEON VEGYESZETI GYAR RT (HU) 1979-10-23 US disclosed