SCHEMBL9848836

SCHEMBL9848836

NC(=O)[C@H](CO)NC(=O)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSL P07711 3/20 0.58
CTSK P43235 4/20 0.54
TACR1 P25103 2/20 0.54
CTRB1 P17538 2/20 0.54
CTSS P25774 3/20 0.53
CTSB P07858 2/20 0.53
CASP1 P29466 3/20 0.52
ALDH1A1 P00352 1/20 0.52
ALOX15 P16050 1/20 0.52
SIRT2 Q8IXJ6 1/20 0.52
KYNU Q16719 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10028352 0.89 ALDH1A1 (0.64) CTSLCTSKTACR1CTRB1CTSS
SCHEMBL13503284 0.89 ALDH1A1 (0.64) CTSLCTSKTACR1CTRB1CTSS
SCHEMBL9848827 0.88 CTSK (0.52) CTSLCTSKTACR1CTRB1CTSS
SCHEMBL10250520 0.88 CTSL (0.68) CTSLCTSKTACR1CTRB1CTSS
SCHEMBL764062 0.88 CTSL (0.68) CTSLCTSKTACR1CTRB1CTSS
SCHEMBL6387189 0.88 CTSL (0.68) CTSLCTSKTACR1CTRB1CTSS
SCHEMBL17446717 0.88 CTSK (0.57) CTSLCTSKTACR1CTRB1CTSS
SCHEMBL201710 0.88 PPARA (0.57) CTSLCTSKTACR1CTRB1CTSS
SCHEMBL295865 0.88 PPARA (0.57) CTSLCTSKTACR1CTRB1CTSS
SCHEMBL2677964 0.88 CTSK (0.57) CTSLCTSKTACR1CTRB1CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157140-A Stable peptides with renal enzymatic agent activity 贝索制药有限责任公司 2023-05-23 CN claimed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
US-20230357501-A1 POLYETHYLENE GLYCOL DERIVATIVE, COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING BIOACTIVE POLYPEPTIDE CONJUGATE BY USING SAME HANMI FINE CHEMICAL CO., LTD. (KR) 2023-11-09 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
EP-4215565-A1 POLYETHYLENE GLYCOL DERIVATIVE, COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING BIOACTIVE POLYPEPTIDE CONJUGATE BY USING SAME Hanmi Fine Chemical Co., Ltd. (KR) 2023-07-26 EP disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022061924-A1 GLP-1R/GCGR DUAL-TARGET AGONIST PEPTIDE DERIVATIVES FOR TREATMENT OF VIRAL HEPATITIS-RELATED HEPATIC FIBROSIS 深圳市图微安创科技开发有限公司 2022-03-31 WO disclosed
WO-2022060131-A1 POLYETHYLENE GLYCOL DERIVATIVE, COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING BIOACTIVE POLYPEPTIDE CONJUGATE BY USING SAME 한미정밀화학 주식회사 2022-03-24 WO disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
EP-0459730-A2 Anti-tumour compounds ZENECA LIMITED (GB) 1991-12-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357501-A1 POLYETHYLENE GLYCOL DERIVATIVE, COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING BIOACTIVE POLYPEPTIDE CONJUGATE BY USING SAME NGLY1, VIP, IAPP CTSL 796/4885CTSK 1439/4885TACR1 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.