SCHEMBL7640644

SCHEMBL7640644

O=C(CC(=O)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LIPA P38571 2/20 0.39
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CA2 P00918 1/20 0.32
HDAC6 Q9UBN7 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2891773 0.91 PLOD2 (0.39) LIPAALDH1A1POLBSMN1; SMN2CA2
SCHEMBL27737984 0.89 PLOD2 (0.38) LIPAALDH1A1POLBSMN1; SMN2CA2
SCHEMBL10005321 0.87 LIPA (0.41) LIPA
SCHEMBL26493734 0.87 LIPA (0.41) LIPA
SCHEMBL1120004 0.87 LIPA (0.41) LIPAKMT2A
SCHEMBL19514016 0.84 LIPA (0.40) LIPA
SCHEMBL5467545 0.83 LIPA (0.38) LIPAALDH1A1POLBSMN1; SMN2CA2
SCHEMBL2221105 0.81 THRB (0.42) THRBCA2
SCHEMBL9292006 0.81 PTPN1 (0.38) LIPATHRB
SCHEMBL7638938 0.79 TDP1 (0.41) LIPAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111479628-B Moisture-curable composition 科思创德国股份有限公司 2024-03-08 CN claimed
US-11834545-B2 Moisture-curing compositions COVESTRO DEUTSCHLAND AG (DE) 2023-12-05 US claimed
EP-3727686-B1 MOISTURE-CURABLE COMPOSITIONS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-05-10 EP claimed
EP-3474046-B1 POLYMERIZABLE COMPOSITION FOR A MAKING A PLASTIC LENS AND PROCESS FOR PREPARING SUCH A LENS SKC CO LTD (KR) 2022-11-30 EP claimed
EP-3357950-B1 POLYMERIZABLE COMPOSITION FOR PLASTIC LENS AND METHOD OF PREPARING PLASTIC LENS USING SAME SKC CO LTD (KR) 2022-01-12 EP claimed
CN-108276555-B Polymerizable composition for plastic lens and method for producing plastic lens using same SKC株式会社 2021-11-05 CN claimed
CN-109293865-B Polymerizable composition for plastic lenses SKC株式会社 2021-09-24 CN claimed
US-10968309-B2 Polymerizable composition for a plastic lens SKC CO., LTD. (KR) 2021-04-06 US claimed
US-20200392278-A1 MOISTURE-CURING COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2020-12-17 US claimed
US-10865307-B2 Polymerizable composition for plastic lens and method of preparing plastic lens using same SKC CO.. LTD. (KR) 2020-12-15 US claimed
EP-3727686-A1 MOISTURE-CURING COMPOSITIONS Covestro Deutschland AG (DE) 2020-10-28 EP claimed
EP-3501641-A1 MOISTURE-CURABLE COMPOSITIONS Covestro Deutschland AG (DE) 2019-06-26 EP claimed
EP-3474046-A1 POLYMERIZABLE COMPOSITION FOR A PLASTIC LENS SKC Co., Ltd. (KR) 2019-04-24 EP claimed
US-20190112414-A1 POLYMERIZABLE COMPOSITION FOR A PLASTIC LENS SK PUCORE CO., LTD. (KR) 2019-04-18 US claimed
US-20180224576-A1 POLYMERIZABLE COMPOSITION FOR PLASTIC LENS AND METHOD OF PREPARING PLASTIC LENS USING SAME SKC CO., LTD. (KR) 2018-08-09 US claimed
EP-3357950-A1 POLYMERIZABLE COMPOSITION FOR PLASTIC LENS AND METHOD OF PREPARING PLASTIC LENS USING SAME SKC Co., Ltd. (KR) 2018-08-08 EP claimed
US-11834545-B2 Moisture-curing compositions COVESTRO DEUTSCHLAND AG (DE) 2023-12-05 US disclosed
EP-3727686-B1 MOISTURE-CURABLE COMPOSITIONS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-05-10 EP disclosed
US-3867418-A EUROPIUM COMPLEX OF 1,1,1,2,2,6,6,7,7,7-DECAFLUORO-3,5-HEPTANEDIONE UNIV IOWA STATE RES FOUND INC 1975-02-18 US disclosed
US-3867418-A EUROPIUM COMPLEX OF 1,1,1,2,2,6,6,7,7,7-DECAFLUORO-3,5-HEPTANEDIONE UNIV IOWA STATE RES FOUND INC 1975-02-18 US disclosed