Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | FGF1 | P05230 | 2/20 | 0.39 |
| ▸ | FGF2 | P09038 | 2/20 | 0.39 |
| ▸ | VEGFA | P15692 | 2/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.39 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640793 | 1.00 | LMNA (0.46) | LMNALGALS9MAPTSLC5A2MCHR1 | |
| SCHEMBL14890384 | 0.84 | FGF1 (0.44) | LMNALGALS9SLC5A2CA1CA2 | |
| SCHEMBL15504371 | 0.81 | SLC5A2 (0.47) | MAPTSLC5A2SYNJ2KDM4EABL1 | |
| SCHEMBL14903579 | 0.81 | SLC5A2 (0.47) | MAPTSLC5A2SYNJ2KDM4EABL1 | |
| SCHEMBL14903581 | 0.81 | SLC5A2 (0.47) | MAPTSLC5A2SYNJ2KDM4EABL1 | |
| SCHEMBL8347457 | 0.81 | CA1 (0.39) | LGALS9SLC5A2CA1CA2CA9 | |
| SCHEMBL8347450 | 0.81 | CA1 (0.39) | LGALS9SLC5A2CA1CA2CA9 | |
| SCHEMBL29193080 | 0.75 | SLC5A2 (0.61) | SLC5A2POLB | |
| SCHEMBL2621543 | 0.75 | SLC5A2 (0.61) | SLC5A2POLB | |
| SCHEMBL26071211 | 0.75 | SYNJ2 (0.51) | MAPTSLC5A2SYNJ2KDM4EABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462193-B1 | ADDING 3-AZIDO-2-HYDROXYPROPANALDEHYDE WITH DIHYDROXYACETONE PHOSPHATE USING AN ALDOLASE, HYDROLYZING THE INTERMEDIATE WITH ACID PHOSPHATASE, ISOMERIZING USING AN ISOMERASE, CYCLIZING USING REDUCTIVE AMINATION TO PRODUCE TETRAHYDROXYAZEPINE | THE SCRIPPS RESEARCH INSTITUTE | 2002-10-08 | — | — | US | disclosed |
| WO-1998037218-A1 | HYDROXYAZEPANES AS INHIBITORS OF GLYCOSIDASE AND HIV PROTEASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-27 | — | — | WO | disclosed |