Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PNLIP | P16233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640794 | 1.00 | MMP9 (0.39) | MMP9LMNATP53PNLIP | |
| SCHEMBL7646655 | 0.85 | MMP9 (0.41) | MMP9LMNATP53 | |
| Allobarbital SCHEMBL1887977 | 0.83 | LMNA (0.50) | MMP9LMNATP53 | |
| SCHEMBL9189636 | 0.81 | TP53 (0.36) | LMNATP53PNLIP | |
| SCHEMBL9189643 | 0.81 | TP53 (0.36) | LMNATP53PNLIP | |
| Allobarbital SCHEMBL35976 | 0.80 | LMNA (0.48) | MMP9LMNATP53 | |
| Allobarbital SCHEMBL11484021 | 0.78 | LMNA (0.46) | MMP9LMNATP53 | |
| Allobarbital SCHEMBL10817112 | 0.75 | MMP9 (0.41) | MMP9LMNATP53 | |
| Etallobarbital SCHEMBL713588 | 0.73 | LMNA (0.64) | MMP9LMNATP53 | |
| SCHEMBL2048015 | 0.73 | MMP9 (0.42) | MMP9LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457213-B1 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LAB (US) | 1997-07-23 | — | — | EP | claimed |
| US-6472227-B1 | A FLUORESCEIN MOIETY IS INCLUDED IN THE TRACER, WHILE A POLY(AMINO ACID) FORMS A PART OF THE IMMUNOGEN FOR DETERMINING THE AMOUNT OF BARBITURATE IN FLUIDS, ESPECIALLY BIOLOGICAL FLUIDS SUCH AS SERUM, PLASMA OR URINE | ABBOTT LABORATORIES | 2002-10-29 | — | — | US | disclosed |
| EP-0457213-B1 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LAB (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0430065-B1 | Barbiturate assay compositions and methods | ABBOTT LAB (US) | 1995-11-15 | — | — | EP | disclosed |
| US-5099020-A | Immunoassay with fluorescent compounds | ABBOTT LABORATORIES (US) | 1992-03-24 | — | — | US | disclosed |
| US-5096838-A | Fluorescent tracers for detection of barbiturates and for antiserums | ABBOTT LABORATORIES (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0457213-A2 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LABORATORIES (US) | 1991-11-21 | — | — | EP | disclosed |
| EP-0430065-A2 | Barbiturate assay compositions and methods | ABBOTT LABORATORIES (US) | 1991-06-05 | — | — | EP | disclosed |