Allobarbital

Allobarbital

SCHEMBL35976

C=CCC1(CC=C)C(=O)NC(=O)NC1=O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
MMP9 P14780 3/20 0.47
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
CPT1A P50416 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MMP2 P08253 2/20 0.30
MMP8 P22894 2/20 0.30
MMP13 P45452 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allobarbital SCHEMBL11484021 0.98 LMNA (0.46) LMNAMMP9TP53GAAHPGD
Allobarbital SCHEMBL10817112 0.89 MMP9 (0.41) LMNAMMP9TP53
Allobarbital SCHEMBL1887977 0.89 LMNA (0.50) LMNAMMP9TP53CPT1AALDH1A1
Etallobarbital SCHEMBL713588 0.87 LMNA (0.64) LMNAMMP9TP53CPT1AALDH1A1
SCHEMBL2048015 0.86 MMP9 (0.42) LMNAMMP9TP53
SCHEMBL2048014 0.86 MMP9 (0.42) LMNAMMP9TP53
Allobarbital SCHEMBL7871535 0.84 MMP9 (0.38) LMNAMMP9TP53
SCHEMBL7646655 0.84 MMP9 (0.41) LMNAMMP9TP53
SCHEMBL5065701 0.83 ALDH1A1 (0.43) LMNAMMP9CPT1AALDH1A1
SCHEMBL2051800 0.82 MMP9 (0.36) MMP9CPT1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4735 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250081863-A1 STRUCTURE TO REGULATE MULTI-FILAMENT FORMATION ON MEMORY STRUCTURE INTERNATIONAL BUSINESS MACHINES CORPORATION 2025-03-06 US claimed
CN-115148900-B Resistance-switching memory device and method for forming a resistance-switching memory device 昕原半导体(上海)有限公司 2025-02-21 CN claimed
US-12161695-B2 GABA A receptor agonists for treatment of disorders influenced by dysfunction BETA cells DIAMYD MEDICAL AB (SE) 2024-12-10 US claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
US-12075712-B2 Resistive switching memory devices and method(s) for forming the resistive switching memory devices Crossbar, Inc. (US) 2024-08-27 US claimed
WO-2024150170-A1 PIROMELATINE FOR TREATING PARASOMNIAS ASSOCIATED WITH LOSS OF REM SLEEP ATONIA NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2024-07-18 WO claimed
US-20240238250-A1 METHOD OF USING PIROMELATINE FOR TREATING PARASOMNIAS ASSOCIATED WITH LOSS OF REM SLEEP ATONIA NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2024-07-18 US claimed
US-11839615-B2 Compounds and methods for treating addiction and related disorders ASTROCYTE PHARMACEUTICALS, INC. (US) 2023-12-12 US claimed
US-20220362160-A1 ABUSE RESISTANT CAPSULE R.P. SCHERER TECHNOLOGIES, LLC (US) 2022-11-17 US claimed
US-11464747-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2022-10-11 US claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0900086-A4 ENHANCEMENT OF SLEEP WITH A GROWTH HORMONE SECRETAGOGUE MERCK & CO INC (US) 2000-01-12 EP claimed
EP-0900086-A1 ENHANCEMENT OF SLEEP WITH A GROWTH HORMONE SECRETAGOGUE Merck & Co., Inc. (US) 1999-03-10 EP claimed
WO-1997041879-A1 ENHANCEMENT OF SLEEP WITH A GROWTH HORMONE SECRETAGOGUE MERCK & CO., INC. (US) 1997-11-13 WO claimed
US-4690824-A Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion: expanded range REDI-ROWELL, INC. (US) 1987-09-01 US claimed
EP-0090966-B1 PROCESS FOR ANTIGEN DETERMINATION AMERICAN HOSPITAL SUPPLY CORPORATION (US) 1985-12-18 EP claimed
US-4458044-A PREVENTION OF FORMATION OF WATER TREES SIEMENS AKTIENGESELLSCHAFT (DE) 1984-07-03 US claimed
US-4382983-A PARTIALLY HYDROLYZED SILOXANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-05-10 US claimed
US-4284707-A Photocurable light-sensitive composition SOMAR MANUFACTURING CO., LTD. (JP) 1981-08-18 US claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed