Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068563 | 0.85 | CES1 (0.32) | LMNAALDH1A1HSD17B10CES1MEN1 | |
| SCHEMBL6280834 | 0.79 | MAPT (0.39) | LMNAALDH1A1HSD17B10CES1MEN1 | |
| SCHEMBL1436952 | 0.79 | LMNA (0.41) | LMNAALDH1A1HSD17B10CES1MEN1 | |
| SCHEMBL30306724 | 0.79 | LMNA (0.41) | LMNAALDH1A1HSD17B10CES1MEN1 | |
| SCHEMBL8661933 | 0.68 | LMNA (0.33) | LMNAALDH1A1HSD17B10CES1MEN1 | |
| SCHEMBL19890588 | 0.67 | PKM (0.36) | LMNAALDH1A1HSD17B10CES1MEN1 | |
| Benzoic Acid SCHEMBL28277571 | 0.65 | TSHR (0.52) | LMNAALDH1A1HSD17B10CES1MEN1 | |
| SCHEMBL28295995 | 0.65 | ALDH1A1 (0.41) | LMNAALDH1A1HSD17B10CES1MEN1 | |
| SCHEMBL3769766 | 0.64 | MEN1 (0.55) | LMNAALDH1A1HSD17B10CES1MEN1 | |
| SCHEMBL10881475 | 0.64 | ALDH1A1 (0.41) | LMNAALDH1A1HSD17B10CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479423-B1 | Process for the preparation of a polyolefin | BASELL POLYOLEFINE GMBH (DE) | 2002-11-12 | — | — | US | disclosed |
| US-6414096-B1 | POLYMERIZING OLEFIN AT SPECIFIED TEMPERATURE AND PRESSURE, IN SOLUTION, IN SUSPENSION OR IN GAS PHASE, AND IN PRESENCE OF CATALYST WHICH CONSISTS ESSENTIALLY OF METALLOCENE AND ALUMINOXANE | BASELL POLYOLEFINE GMBH (DE) | 2002-07-02 | — | — | US | disclosed |
| EP-0413326-B1 | Process for preparing a polyolefin | HOECHST AG (DE) | 1995-03-08 | — | — | EP | disclosed |
| EP-0413326-A2 | Process for preparing a polyolefin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | disclosed |