Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FER | P16591 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159065 | 0.89 | P2RX7 (0.40) | P2RX7HCRTR2HCRTR1GABRA1GABRG2 | |
| SCHEMBL28738711 | 0.83 | PPARG (0.35) | P2RX7HCRTR2HCRTR1SYKTAS2R14 | |
| SCHEMBL32682038 | 0.80 | KMT2A (0.46) | P2RX7LOXL2TAS2R14 | |
| SCHEMBL22397018 | 0.80 | KMT2A (0.46) | P2RX7LOXL2TAS2R14 | |
| SCHEMBL17117512 | 0.78 | P2RX7 (0.45) | P2RX7HCRTR2HCRTR1GABRA1GABRG2 | |
| SCHEMBL1132769 | 0.76 | TAS2R14 (0.37) | P2RX7HCRTR2HCRTR1SYKTAS2R14 | |
| SCHEMBL30748265 | 0.76 | TAS2R14 (0.37) | P2RX7HCRTR2HCRTR1SYKTAS2R14 | |
| SCHEMBL1132765 | 0.76 | TAS2R14 (0.37) | P2RX7HCRTR2HCRTR1SYKTAS2R14 | |
| SCHEMBL17109775 | 0.76 | P2RX7 (0.43) | P2RX7HCRTR2HCRTR1HTR1AKCNH2 | |
| SCHEMBL20427990 | 0.75 | P2RX7 (0.42) | P2RX7HCRTR2HCRTR1HTR1ARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | disclosed |