Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16065053 | 1.00 | KMT2A (0.53) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL5870043 | 0.82 | KMT2A (0.55) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL764136 | 0.82 | KMT2A (0.55) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL5870048 | 0.82 | KMT2A (0.55) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL18828775 | 0.78 | ALDH1A1 (0.38) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL25647571 | 0.74 | MEN1 (0.37) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL762458 | 0.74 | KMT2A (0.54) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL13906650 | 0.74 | LMNA (0.44) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL4883097 | 0.73 | SMN1; SMN2 (0.40) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL8364996 | 0.73 | SMN1; SMN2 (0.40) | KMT2AALDH1A1MEN1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |