Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057437 | 0.94 | HTR6 (0.52) | HTR6SMN1; SMN2TSHRALDH1A1POLB | |
| SCHEMBL8429342 | 0.87 | GAA (0.50) | HTR6SMN1; SMN2TSHRALDH1A1POLB | |
| SCHEMBL8046886 | 0.81 | HTR6 (0.45) | HTR6SMN1; SMN2TSHRALDH1A1POLB | |
| SCHEMBL15030401 | 0.80 | CNR1 (0.42) | HSD11B1HTR2CHTR2BHTR2AKCNH2 | |
| SCHEMBL1516456 | 0.79 | TSHR (0.58) | HTR6SMN1; SMN2TSHRALDH1A1POLB | |
| SCHEMBL30084548 | 0.79 | ALDH1A1 (0.48) | SMN1; SMN2TSHRALDH1A1POLBLMNA | |
| SCHEMBL5409149 | 0.79 | ALDH1A1 (0.48) | SMN1; SMN2TSHRALDH1A1POLBLMNA | |
| SCHEMBL5080047 | 0.79 | TSHR (0.80) | HTR6SMN1; SMN2TSHRALDH1A1POLB | |
| SCHEMBL15030546 | 0.78 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1POLBMAPTHSD11B1 | |
| SCHEMBL415483 | 0.78 | SMN1; SMN2 (0.62) | HTR6SMN1; SMN2TSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6433050-B1 | SILICONE, METAL SALT OF AROMATIC SULFUR-CONTAINING COMPOUND OR PERFLUOROALKYLSULFONATE, AND FILM-FORMING FLUOROPOLYMER; IMPACT STRENGTH, MOLDABILITY; BROMINE AND CHLORINE-FREE; ENVIRONMENT | SUMITOMO DOW LIMITED (JP) | 2002-08-13 | — | — | US | claimed |