Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | FLT1 | P17948 | 3/20 | 0.35 |
| ▸ | TEK | Q02763 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642157 | 1.00 | NSD3 (0.41) | NSD3KMT2AKDM4EMEN1KDR | |
| SCHEMBL4594720 | 0.74 | BRD4 (0.45) | NSD3KMT2AKDM4EPDE3BPDE3A | |
| SCHEMBL7646136 | 0.71 | LPO (0.40) | KMT2AKDM4ELPO | |
| SCHEMBL7646141 | 0.71 | LPO (0.40) | KMT2AKDM4ELPO | |
| SCHEMBL786747 | 0.69 | HDAC4 (0.52) | KMT2AKDM4EMEN1LPOCHEK1 | |
| SCHEMBL5921550 | 0.67 | HDAC4 (0.51) | KMT2AKDM4EMEN1LPOCHEK1 | |
| Hydrochloric Acid SCHEMBL28830016 | 0.67 | HDAC4 (0.51) | KMT2AKDM4EMEN1LPOCHEK1 | |
| SCHEMBL7642769 | 0.67 | LPO (0.36) | LPOAURKB | |
| SCHEMBL7642764 | 0.67 | LPO (0.36) | LPOAURKB | |
| SCHEMBL9281044 | 0.66 | HDAC4 (0.54) | KMT2AKDM4ECDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002074267-A1 | NOVEL DYEING COMPOSITIONS FOR THE DYEING OF KERATIN FIBRES COMPRISING 6-MEMBERED HETEROCYCLIC HYDRAZONE COMPOUNDS AS AN OXIDATION BASE | L'OREAL (FR) | 2002-09-26 | — | — | WO | disclosed |