SCHEMBL7642641

SCHEMBL7642641

C[Si](C)(C)C1([Si](C)(C)C)C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OXTR P30559 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17296057 0.80 OXTR (0.30) OXTR
Hydrochloric Acid SCHEMBL8034617 0.75 OXTR (0.31) OXTRKDM4EPKM
Hydrochloric Acid SCHEMBL8034608 0.74 OXTR (0.31) OXTRKDM4EPKM
SCHEMBL7779537 0.74 KDM4E (0.37) OXTRKDM4EPKM
SCHEMBL7781719 0.72 OXTR (0.30) OXTR
SCHEMBL7779533 0.72 OXTR (0.30) OXTR
SCHEMBL8034614 0.71 OXTR (0.32) OXTR
SCHEMBL7642038 0.71
SCHEMBL29387054 0.70 KDM4E (0.39) OXTRKDM4EPKMGAAMAPT
SCHEMBL251287 0.70 KDM4E (0.39) OXTRKDM4EPKMGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3148938-A1 METALLIC COMPLEX CATALYST, POLYMERIZATION METHODS EMPLOYING SAME AND POLYMER PRODUCTS THEREOF Bridgestone Corporation (JP) 2017-04-05 EP disclosed
WO-2015183781-A1 METALLIC COMPLEX CATALYST, POLYMERIZATION METHODS EMPLOYING SAME AND POLYMER PRODUCTS THEREOF BRIDGESTONE CORPORATION (JP) 2015-12-03 WO disclosed
EP-0912585-B1 METALLOCENE COMPOUNDS BAYER AG (DE) 2002-04-10 EP disclosed
US-6191241-B1 Method for producing high melting-point polyolefins BAYER AKTIENGESELLSCHAFT (DE) 2001-02-20 US disclosed
US-6184320-B1 AS POLYMERIZATION CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 2001-02-06 US disclosed
US-6174974-B1 CATALYTIC POLYMERIZATION OF MONOMERS FOR POLYMERS WITH TRANSISTION METAL BAYER AKTIENGESELLSCHAFT (DE) 2001-01-16 US disclosed
US-6172169-B1 Method for producing elastomers BAYER AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-6156857-A Method for producing cycloolefin (co)polymers for technical applications BAYER AKTIENGESELLSCHAFT (DE) 2000-12-05 US disclosed
EP-0909282-B1 METHOD FOR PRODUCING CYCLOOLEFIN (CO)POLYMERS FOR TECHNICAL APPLICATIONS BAYER AG (DE) 2000-05-10 EP disclosed
EP-0909281-B1 METHOD FOR PRODUCING ELASTOMERS BAYER AG (DE) 2000-05-10 EP disclosed
EP-0909284-B1 METHOD FOR PRODUCING THERMOPLASTIC ELASTOMERS BAYER AG (DE) 2000-02-02 EP disclosed
EP-0912585-A1 METALLOCENE COMPOUNDS BAYER AG (DE) 1999-05-06 EP disclosed
EP-0909281-A1 METHOD FOR PRODUCING ELASTOMERS BAYER AG (DE) 1999-04-21 EP disclosed
EP-0909283-A1 METHOD FOR PRODUCING HIGH MELTING-POINT POLYOLEFINS BAYER AG (DE) 1999-04-21 EP disclosed
WO-1998001487-A9 METHOD FOR PRODUCING ELASTOMERS 1998-07-02 WO disclosed
WO-1998001486-A9 METHOD FOR PRODUCING THERMOPLASTIC ELASTOMERS 1998-03-26 WO disclosed
WO-1998001455-A1 METALLOCENE COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1998-01-15 WO disclosed
WO-1998001485-A1 METHOD FOR PRODUCING HIGH MELTING-POINT POLYOLEFINS BAYER AKTIENGESELLSCHAFT (DE) 1998-01-15 WO disclosed
WO-1998001487-A1 METHOD FOR PRODUCING ELASTOMERS BAYER AKTIENGESELLSCHAFT (DE) 1998-01-15 WO disclosed
US-4962253-A Vinylation of aromatics catalyzed by cyclopentadienyl, indenyl, or fluorenyl rhodium complexes, and novel indenyl and fluorenyl rhodium complexes THE DOW CHEMICAL COMPANY (US) 1990-10-09 US disclosed