SCHEMBL7779537

SCHEMBL7779537

C[Si](C)(C)C1(CCC2([Si](C)(C)C)C=Cc3ccccc32)C=Cc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
PKM P14618 1/20 0.37
OXTR P30559 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5176382 0.75 SIGMAR1 (0.35) KDM4EPKM
SCHEMBL7642641 0.74 OXTR (0.33) KDM4EPKMOXTR
Hydrochloric Acid SCHEMBL8034617 0.71 OXTR (0.31) KDM4EPKMOXTR
Hydrochloric Acid SCHEMBL8034608 0.69 OXTR (0.31) KDM4EPKMOXTR
SCHEMBL7570416 0.68 SIGMAR1 (0.33)
SCHEMBL7779533 0.68 OXTR (0.30) OXTR
SCHEMBL7781719 0.68 OXTR (0.30) OXTR
SCHEMBL4660513 0.67 KDM4E (0.37) KDM4EPKMOXTR
SCHEMBL7642038 0.67
SCHEMBL8034614 0.67 OXTR (0.32) OXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722950-B1 Process for the preparation of bridged metallocenes BASELL TECHNOLOGY CO BV (NL) 2001-09-12 EP claimed
US-5968863-A REACTION OF LIGAND WITH DOUBLE ANION FOR POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1999-10-19 US claimed
EP-0722950-A1 Process for the preparation of bridged metallocenes Montell Technology Company bv (NL) 1996-07-24 EP claimed
EP-0722950-B1 Process for the preparation of bridged metallocenes BASELL TECHNOLOGY CO BV (NL) 2001-09-12 EP disclosed
US-5968863-A REACTION OF LIGAND WITH DOUBLE ANION FOR POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1999-10-19 US disclosed
EP-0722950-A1 Process for the preparation of bridged metallocenes Montell Technology Company bv (NL) 1996-07-24 EP disclosed