SCHEMBL7642845

SCHEMBL7642845

C=CCOC(=O)C(CCCC)Oc1ccccc1C=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.38
CYP3A4 P08684 2/20 0.38
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
ALDH1A1 P00352 4/20 0.37
HPGD P15428 2/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 3/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
PTGS2 P35354 2/20 0.35
KDM4E B2RXH2 1/20 0.35
RECQL P46063 1/20 0.35
CA2 P00918 1/20 0.34
CTSK P43235 2/20 0.34
RAD52 P43351 1/20 0.34
PTGES O14684 1/20 0.34
ALOX5 P09917 1/20 0.34
PPARG P37231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11755152 0.88 TDP1 (0.42) PTGDR2CYP3A4ALDH1A1HPGDHTT
SCHEMBL6459702 0.85 PTGDR2 (0.41) PTGDR2CYP3A4ALDH1A1HPGDHTT
SCHEMBL19632878 0.83 PTGDR2 (0.40) PTGDR2CYP3A4ALDH1A1HPGDHTT
SCHEMBL19632625 0.83 PTGDR2 (0.40) PTGDR2CYP3A4ALDH1A1HPGDHTT
SCHEMBL6235795 0.82 PPARG (0.49) PTGDR2ALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL7643417 0.81 ERN1 (0.38) ALDH1A1HTTSMN1; SMN2MEN1KMT2A
SCHEMBL19632619 0.81 PPARA (0.45) PTGDR2CYP3A4ALDH1A1HPGDHTT
SCHEMBL19633026 0.81 PPARA (0.45) PTGDR2CYP3A4ALDH1A1HPGDHTT
SCHEMBL25757370 0.78 CTRC (0.47) PTGDR2THRATHRBALDH1A1HPGD
SCHEMBL897268 0.75 ALDH1A1 (0.49) PTGDR2THRBALDH1A1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002255954-A METHOD FOR PRODUCING 2-n-BUTYL-5-NITROBENZOFURAN ISHINO YOSHIO 2002-09-11 JP disclosed