Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755152 | 0.90 | TDP1 (0.42) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL6235795 | 0.86 | PPARG (0.49) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL7642845 | 0.85 | PTGDR2 (0.38) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2329831 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CTSKLMNACYP1A2 | |
| SCHEMBL25757370 | 0.82 | CTRC (0.47) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL5671783 | 0.81 | MGLL (0.37) | ALDH1A1HPGDCA2CA1KDM4E | |
| SCHEMBL5695157 | 0.80 | CYP1A2 (0.47) | ALDH1A1HTTSMN1; SMN2TSHRCA2 | |
| SCHEMBL5695165 | 0.80 | KDM4E (0.55) | ALDH1A1HPGDHTTTSHRCA2 | |
| SCHEMBL14634320 | 0.80 | RORC (0.40) | ALDH1A1HPGDHTTSMN1; SMN2TSHR | |
| SCHEMBL6459325 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HTTSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448503-A1 | PROCESS FOR THE PREPARATION OF BENZOFURANS | Cambrex Profarmaco Milano S.r.l. (IT) | 2024-10-23 | — | — | EP | claimed |
| WO-2023110528-A1 | PROCESS FOR THE PREPARATION OF BENZOFURANS | CAMBREX PROFARMACO MILANO S.R.L. (IT) | 2023-06-22 | — | — | WO | claimed |
| EP-4448503-A1 | PROCESS FOR THE PREPARATION OF BENZOFURANS | Cambrex Profarmaco Milano S.r.l. (IT) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023110528-A1 | PROCESS FOR THE PREPARATION OF BENZOFURANS | CAMBREX PROFARMACO MILANO S.R.L. (IT) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023110528-A1 | PROCESS FOR THE PREPARATION OF BENZOFURANS | CAMBREX PROFARMACO MILANO S.R.L. (IT) | 2023-06-22 | — | — | WO | disclosed |
| CN-114539193-A | Preparation method of amiodarone hydrochloride intermediate | 海南普利制药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108675972-B | Preparation method of amiodarone hydrochloride intermediate 2-butyl benzofuran | 北京嘉林药业股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-7312345-B2 | Process for the preparation of dronedarone | ISP INVESTMENTS INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-20050113596-A1 | Nitrating a 2-(2-formylphenoxy) or 2-(2-formylphenylsulfido) alkyl ester or alkoic acid in the presence of sulfuric acid | SHASUN PHARMA SOLUTIONS, INC. | 2005-05-26 | — | — | US | disclosed |
| US-6855842-B1 | Intermediates for making a bezofuran or benzothiophene derivative nitrated in position 5 and uses thereof | RHODIA CHIMIE (FR) | 2005-02-15 | — | — | US | disclosed |
| US-6555697-B1 | Cyclizing a 1-(2-carboxyethyloxy or thio-),2-formylbenzene in the presence of an efficient amount of a carbonate base in a medium comprising a carboxylic acid anhydride; intermediate for 2-n-butyl-5-nitrobenzofuran | RHODIA CHIMIE (FR) | 2003-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113596-A1 | Nitrating a 2-(2-formylphenoxy) or 2-(2-formylphenylsulfido) alkyl ester or alkoic acid in the presence of sulfuric acid | SULT1A1, SULT1E1, FPR1 | PTGDR2 1817/4885ALDH1A1 111/4885HPGD 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.