Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4549061 | 1.00 | THRB (0.60) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL238953 | 0.91 | THRB (0.70) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12472236 | 0.88 | THRB (0.58) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL14764557 | 0.87 | THRB (0.62) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Alcohol SCHEMBL7030010 | 0.87 | ALDH1A1 (0.68) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL7642880 | 0.87 | THRB (0.67) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL14130577 | 0.87 | ALDH1A1 (0.67) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28543752 | 0.87 | THRB (0.70) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL6299224 | 0.86 | THRB (0.57) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene Glycol SCHEMBL10426882 | 0.85 | ALDH1A1 (0.66) | THRBALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2199273-B1 | Polymerizable photoinitiators and radiation curable compositions | AGFA NV (BE) | 2018-02-21 | — | — | EP | disclosed |
| EP-2684876-B1 | Polymerizable thioxanthones | AGFA GRAPHICS NV (BE) | 2016-09-14 | — | — | EP | disclosed |
| EP-2444429-B1 | LED CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2016-09-07 | — | — | EP | disclosed |
| EP-2447259-B1 | Polymerisable photoinitiators for LED curable compositions | AGFA GRAPHICS NV (BE) | 2016-03-16 | — | — | EP | disclosed |
| US-9278949-B2 | Polymerizable thioxanthones | AGFA GRAPHICS NV (BE) | 2016-03-08 | — | — | US | disclosed |
| US-9278949-B2 | Polymerizable thioxanthones | AGFA GRAPHICS NV (BE) | 2016-03-08 | — | — | US | disclosed |
| US-20150158839-A1 | POLYMERIZABLE THIOXANTHONES | AGFA NV (BE) | 2015-06-11 | — | — | US | disclosed |
| US-20150158839-A1 | POLYMERIZABLE THIOXANTHONES | AGFA NV (BE) | 2015-06-11 | — | — | US | disclosed |
| US-8985753-B2 | LED curable compositions | AGFA GRAPHICS NV (BE) | 2015-03-24 | — | — | US | disclosed |
| US-8985753-B2 | LED curable compositions | AGFA GRAPHICS NV (BE) | 2015-03-24 | — | — | US | disclosed |
| EP-2447259-A1 | Polymerisable photoinitiators for LED curable compositions | Agfa-Gevaert (BE) | 2012-05-02 | — | — | EP | disclosed |
| WO-2012052288-A1 | POLYMERISABLE PHOTOINITIATORS FOR LED CURABLE COMPOSITIONS | AGFA-GEVAERT (BE) | 2012-04-26 | — | — | WO | disclosed |
| EP-2444429-A1 | Led curable compositions | Agfa-Gevaert (BE) | 2012-04-25 | — | — | EP | disclosed |
| US-20120046376-A1 | POLYMERIZABLE POLYMERIC PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2012-02-23 | — | — | US | disclosed |
| US-20120046376-A1 | POLYMERIZABLE POLYMERIC PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2012-02-23 | — | — | US | disclosed |
| US-20110224324-A1 | POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2011-09-15 | — | — | US | disclosed |
| US-20110224324-A1 | POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2011-09-15 | — | — | US | disclosed |
| WO-2010133381-A1 | POLYMERIZABLE POLYMERIC PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010069758-A1 | POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2010-06-24 | — | — | WO | disclosed |
| EP-2199273-A1 | Polymerizable photoinitiators and radiation curable compositions | AGFA Graphics NV (BE) | 2010-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158839-A1 | POLYMERIZABLE THIOXANTHONES | HADHA, TST, ASS1 | THRB 1611/4885ALDH1A1 53/4885TP53 746/4885 |
| US-20110224324-A1 | POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | WEE1, ZYX, MTR | THRB 3019/4885ALDH1A1 632/4885TP53 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.