Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL927212 | 0.95 | LOXL2 (0.56) | LOXL2NPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL13984517 | 0.91 | LOXL2 (0.51) | LOXL2NPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3021137 | 0.87 | PTPN11 (0.49) | LOXL2NPC1SMN1; SMN2ALDH1A1KDM4E | |
| Cyclohexane SCHEMBL7643203 | 0.83 | RXRA (0.46) | NPC1SMN1; SMN2ALDH1A1RAB9AKMT2A | |
| SCHEMBL121593 | 0.80 | LOXL2 (0.58) | LOXL2NPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2607023 | 0.79 | LOXL2 (0.66) | LOXL2NPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL16867358 | 0.79 | LOXL2 (0.53) | LOXL2NPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3480024 | 0.77 | KMT2A (0.42) | HPGDMEN1KMT2A | |
| SCHEMBL29387017 | 0.77 | CA1 (0.70) | LOXL2NPC1SMN1; SMN2ALDH1A1TSHR | |
| Cyclohexane SCHEMBL1133519 | 0.77 | CA1 (0.70) | LOXL2NPC1SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458468-B1 | VINYL ETHER OLIGOMER, PHOTOINITIATOR AND ACRYLATE AND/OR EPOXY COMPOUND; CHEMICAL RESISTANT PROTECTIVE COATINGS; STRESS RESISTANCE, NONCRACKING | EASTMAN CHEMICAL COMPANY | 2002-10-01 | — | — | US | claimed |