Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.46 |
| ▸ | RXRB | P28702 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129810 | 0.92 | ALDH1A1 (0.50) | RXRARXRBNPC1RAB9APOLB | |
| SCHEMBL7643725 | 0.84 | KMT2A (0.45) | RXRARXRBNPC1RAB9APOLB | |
| Cyclohexane SCHEMBL7643198 | 0.83 | LOXL2 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL927212 | 0.77 | LOXL2 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5116479 | 0.75 | ALDH1A1 (0.51) | RXRARXRBNPC1RAB9APOLB | |
| Terephthalic Acid SCHEMBL6906820 | 0.75 | ALDH1A1 (0.50) | RXRARXRBSMN1; SMN2ALDH1A1PLA2G4B | |
| SCHEMBL566413 | 0.75 | NPC1 (0.62) | RXRARXRBNPC1RAB9APOLB | |
| Terephthalic Acid SCHEMBL29170961 | 0.74 | TSHR (0.71) | SMN1; SMN2ALDH1A1 | |
| Terephthalic Acid SCHEMBL246842 | 0.74 | TSHR (0.71) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL5479582 | 0.74 | IDO1 (0.35) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458468-B1 | VINYL ETHER OLIGOMER, PHOTOINITIATOR AND ACRYLATE AND/OR EPOXY COMPOUND; CHEMICAL RESISTANT PROTECTIVE COATINGS; STRESS RESISTANCE, NONCRACKING | EASTMAN CHEMICAL COMPANY | 2002-10-01 | — | — | US | claimed |