Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25C | P30307 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128408 | 0.97 | GPR3 (0.40) | GPR3NTRK1KMT2ALMNACDC25A | |
| SCHEMBL7128806 | 0.80 | KDM4E (0.43) | KMT2ALMNAKDM4EALDH1A1MAPT | |
| SCHEMBL7129142 | 0.77 | NTRK1 (0.38) | GPR3NTRK1KMT2ALMNAKDM4E | |
| SCHEMBL7643266 | 0.75 | PNMT (0.31) | — | |
| SCHEMBL7126885 | 0.75 | GPR3 (0.41) | GPR3NTRK1KMT2ALMNACDC25A | |
| SCHEMBL7124307 | 0.75 | GPR3 (0.41) | GPR3NTRK1LMNACDC25ACDC25C | |
| SCHEMBL7638144 | 0.75 | GPR3 (0.41) | GPR3NTRK1KMT2ALMNACDC25A | |
| SCHEMBL7125690 | 0.74 | GPR3 (0.38) | GPR3NTRK1LMNACDC25ACDC25C | |
| SCHEMBL5837267 | 0.74 | GPR3 (0.46) | GPR3KMT2AALDH1A1MEN1IDO1 | |
| Hydrochloric Acid SCHEMBL7126873 | 0.74 | GPR3 (0.40) | GPR3NTRK1KMT2ALMNACDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451724-B1 | BIS(N-METHYL-5,10-DIHYDROINDENO(1,2-B)INDOL-10 -YL)TITANIUM DICHLORIDE | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-09-17 | — | — | US | disclosed |