SCHEMBL7643266

SCHEMBL7643266

Cn1c2c(c3ccccc31)-c1ccccc1C2C(C)(C)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7129138 0.84 WDR5 (0.31) PNMTNPC1RAB9A
SCHEMBL7125688 0.77 PNMT (0.30) PNMTNPC1RAB9A
SCHEMBL7128408 0.77 GPR3 (0.40)
SCHEMBL7121839 0.77
Hydrochloric Acid SCHEMBL7121843 0.75 PNMT (0.33) PNMTNPC1RAB9A
SCHEMBL7643270 0.75 GPR3 (0.38)
SCHEMBL7635165 0.74
Hydrochloric Acid SCHEMBL7120799 0.74
SCHEMBL7635162 0.73
SCHEMBL7120795 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6451724-B1 BIS(N-METHYL-5,10-DIHYDROINDENO(1,2-B)INDOL-10 -YL)TITANIUM DICHLORIDE BASELL TECHNOLOGY COMPANY BV (NL) 2002-09-17 US disclosed