Fluoride Ion

Fluoride Ion

SCHEMBL7643349

CC1=Cc2c(ccc3ccccc23)C1[Zr+2]C1C(C)=Cc2c1ccc1ccccc21.[F-].[F-]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.38
CYP2A6 P11509 3/20 0.38
KDM4E B2RXH2 3/20 0.37
TSHR P16473 3/20 0.36
CYP1A2 P05177 3/20 0.36
HSD17B10 Q99714 6/20 0.35
TDP1 Q9NUW8 2/20 0.35
HPGD P15428 4/20 0.35
HIF1A Q16665 2/20 0.33
HPRT1 P00492 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
RAB9A P51151 1/20 0.33
CASP7 P55210 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 4/20 0.32
ALOX12 P18054 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8853408 0.97 ALDH1A1 (0.38) ALDH1A1CYP2A6KDM4ETSHRCYP1A2
Hydrochloric Acid SCHEMBL2522928 0.97 ALDH1A1 (0.38) ALDH1A1CYP2A6KDM4ETSHRCYP1A2
Hydrochloric Acid SCHEMBL9063494 0.90 KDM4E (0.34) ALDH1A1CYP2A6KDM4ETSHRCYP1A2
Hydrochloric Acid SCHEMBL7935633 0.87 KDM4E (0.33) ALDH1A1CYP2A6KDM4ETSHRCYP1A2
Hydrochloric Acid SCHEMBL8628885 0.85 TNF (0.35) ALDH1A1CYP2A6KDM4ETSHRHSD17B10
Fluoride Ion SCHEMBL7639237 0.84 CA12 (0.36) ALDH1A1CYP2A6KDM4EHPGDMAPK1
Hydrochloric Acid SCHEMBL8853186 0.83 KDM4E (0.32) ALDH1A1CYP2A6KDM4EHSD17B10HPGD
Hydrochloric Acid SCHEMBL3789707 0.83 KDM4E (0.38) ALDH1A1CYP2A6KDM4ETSHRCYP1A2
Hydrochloric Acid SCHEMBL2525067 0.81 CA12 (0.36) ALDH1A1CYP2A6KDM4EHPGDMAPK1
Hydrochloric Acid SCHEMBL5689511 0.81 KDM4E (0.37) ALDH1A1CYP2A6KDM4ETSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020143125-A1 Catalyst component and catalyst system having a high polymerization activity for preparing polymers KAMINSKY WALTER (DE) 2002-10-03 US disclosed
US-6303718-B1 PARTICULARLY A CATALYST SYSTEM CONSISTING OF METALLOCENE FLUORIDES AND ALUMINUM ALKYLS BAYER AKTIENGESELLSCHAFT (DE) 2001-10-16 US disclosed