SCHEMBL7643395

SCHEMBL7643395

CC=C(C)CCC=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.46
IDO1 P14902 2/20 0.46
PAM P19021 1/20 0.46
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
HTR2A P28223 3/20 0.43
GLA P06280 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11654875 0.82 ALDH1A1 (0.46) SIGMAR1PAMHDAC3HDAC4HDAC1
SCHEMBL11697036 0.82 ALDH1A1 (0.46) SIGMAR1PAMHDAC3HDAC4HDAC1
SCHEMBL3108113 0.81 PAM (0.55) SIGMAR1PAMHDAC3HDAC4HDAC1
SCHEMBL27997223 0.81 SIGMAR1 (0.46) SIGMAR1IDO1PAMHDAC3HDAC4
SCHEMBL3108116 0.81 PAM (0.55) SIGMAR1PAMHDAC3HDAC4HDAC1
SCHEMBL25909671 0.79 PAM (0.49) SIGMAR1PAMHDAC3HDAC4HDAC1
Water SCHEMBL7165212 0.78 PAM (0.57) SIGMAR1IDO1PAMHTR2AGLA
SCHEMBL11480382 0.76 PPARG (0.44) SIGMAR1PAMHDAC3HDAC4HDAC1
SCHEMBL11480385 0.76 PPARG (0.44) SIGMAR1PAMHDAC3HDAC4HDAC1
SCHEMBL7939387 0.76 IDO1 (0.56) SIGMAR1IDO1PAMHTR2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131995-B1 POLYOLEFIN-BASED HOT MELT ADHESIVES WITH IMPROVED PROPERTIES BOSTIK INC (US) 2018-06-06 EP claimed
US-6476131-B1 Self-reinforced rubber matrix having high glass transition temperature thermoset domains THE UNIVERSITY OF AKRON 2002-11-05 US claimed
WO-2001019917-A1 A SELF-REINFORCED RUBBER MATRIX HAVING HIGH GLASS TRANSITION TEMPERATURE THERMOSET DOMAINS THE UNIVERSITY OF AKRON (US) 2001-03-22 WO claimed
US-4766049-A STABILIZED POLYMER LATEX WITH IMBIBED MOLECULARY DISPERSED COLORED DYE, AND THICKENER XEROX CORPORATION (US) 1988-08-23 US claimed
EP-3131995-B1 POLYOLEFIN-BASED HOT MELT ADHESIVES WITH IMPROVED PROPERTIES BOSTIK INC (US) 2018-06-06 EP disclosed
EP-3131995-A1 POLYOLEFIN-BASED HOT MELT ADHESIVES WITH IMPROVED PROPERTIES Bostik, Inc. (US) 2017-02-22 EP disclosed
WO-2015161039-A1 POLYOLEFIN-BASED HOT MELT ADHESIVES WITH IMPROVED PROPERTIES BOSTIK, INC. (US) 2015-10-22 WO disclosed
US-20150299526-A1 Polyolefin-Based Hot Melt Adhesives With Improved Properties BOSTIK, INC. (US) 2015-10-22 US disclosed
EP-2643413-A1 CONTROLLING MORPHOLOGY OF BLOCK COPOLYMERS Dow Corning Corporation (US) 2013-10-02 EP disclosed
WO-2012071330-A1 CONTROLLING MORPHOLOGY OF BLOCK COPOLYMERS DOW CORNING CORPORATION (US) 2012-05-31 WO disclosed
US-6476131-B1 Self-reinforced rubber matrix having high glass transition temperature thermoset domains THE UNIVERSITY OF AKRON 2002-11-05 US disclosed
WO-2001019917-A1 A SELF-REINFORCED RUBBER MATRIX HAVING HIGH GLASS TRANSITION TEMPERATURE THERMOSET DOMAINS THE UNIVERSITY OF AKRON (US) 2001-03-22 WO disclosed
US-4766049-A STABILIZED POLYMER LATEX WITH IMBIBED MOLECULARY DISPERSED COLORED DYE, AND THICKENER XEROX CORPORATION (US) 1988-08-23 US disclosed