Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206421 | 0.85 | MEN1 (0.45) | LMNAMEN1KMT2AHPGDNPC1 | |
| Methylamine SCHEMBL1207581 | 0.83 | MEN1 (0.43) | LMNAMEN1KMT2AHPGDNPC1 | |
| SCHEMBL14539771 | 0.83 | KDM4E (0.44) | LMNAMEN1KMT2AHPGDNPC1 | |
| SCHEMBL5165003 | 0.81 | MMP1 (0.46) | LMNAMEN1KMT2AHPGDNPC1 | |
| SCHEMBL1207584 | 0.79 | LMNA (0.44) | LMNAMEN1KMT2AHPGDNPC1 | |
| SCHEMBL338839 | 0.76 | RIPK1 (0.46) | MEN1KMT2AALDH1A1MMP1MMP7 | |
| SCHEMBL15486359 | 0.75 | MEN1 (0.45) | LMNAMEN1KMT2AHPGDNPC1 | |
| SCHEMBL19331149 | 0.75 | HPGD (0.45) | LMNAMEN1KMT2AHPGDNPC1 | |
| SCHEMBL338494 | 0.75 | KMT2A (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL338594 | 0.75 | MEN1 (0.49) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476229-B1 | Processes for the manufacturing of 3-hydroxy-N,1,6-trialkyl-4-oxo-1,4-dihydropyridine-2-carboxamide | APOTEX, INC. (CA) | 2002-11-05 | — | — | US | disclosed |
| US-6472532-B1 | INEXPENSIVE METHOD USING KOJIC ACID AS SAFE STARTING MATERIAL FOR SYNTHESIS OF ORALLY ACTIVE IRON CHELATORS | APOTEX, INC. (CA) | 2002-10-29 | — | — | US | disclosed |
| US-6426418-B1 | REACTING A 3-OXY-2-HYDROXYALKYL-4H-PYRAN-4-ONE DERIVATIVE WITH SODIUM HYPOCHLORITE SOLUTION, POTASSIUM BROMIDE, TEMPO, AND A PHASE TRANSFER CATALYST TO PRODUCE A 3-OXY-2-CARBOXY-4H-PYRAN-4-ONE DERIVATIVE | APOTEX, INC. (CA) | 2002-07-30 | — | — | US | disclosed |