Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643840 | 1.00 | KDM4E (0.53) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL11621235 | 0.79 | MEN1 (0.61) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL28566718 | 0.79 | MEN1 (0.61) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL7641392 | 0.77 | MEN1 (0.55) | MEN1NPC1KMT2AENPP2 | |
| SCHEMBL7641390 | 0.77 | MEN1 (0.55) | MEN1NPC1KMT2AENPP2 | |
| SCHEMBL23169425 | 0.77 | GLO1 (0.43) | MEN1NPC1MAPTKMT2A | |
| SCHEMBL6948762 | 0.77 | MEN1 (0.64) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL11911194 | 0.76 | ENPP2 (0.49) | MEN1MAPTKMT2AENPP2 | |
| SCHEMBL5982552 | 0.76 | MEN1 (0.76) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL30586344 | 0.76 | MEN1 (0.76) | KDM4EMEN1NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448238-B1 | BORONIC ACIDS USED WITH BETA-LACTAM ANTIBIOTICS, SUCH AS AMOXICILLIN OR CEFTAZIDIME, TO TREAT BETA-LACTAM ANTIBIOTIC RESISTANT BACTERIAL INFECTIONS | NORTHWESTERN UNIVERSITY | 2002-09-10 | — | — | US | claimed |
| US-6448238-B1 | BORONIC ACIDS USED WITH BETA-LACTAM ANTIBIOTICS, SUCH AS AMOXICILLIN OR CEFTAZIDIME, TO TREAT BETA-LACTAM ANTIBIOTIC RESISTANT BACTERIAL INFECTIONS | NORTHWESTERN UNIVERSITY | 2002-09-10 | — | — | US | disclosed |
| US-6184363-B1 | Inhibitors of β-lactamases and uses therefor | NORTHWESTERN UNIVERSITY | 2001-02-06 | — | — | US | disclosed |
| EP-0596700-A1 | Cis-diol detection method and solid supports | Hewlett-Packard Company (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5108502-A | Azo dyes; water solubility; utility in inks for ink-jet printing | HEWLETT-PACKARD COMPANY (US) | 1992-04-28 | — | — | US | disclosed |