Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7644118

CC(C)=[Zr+2](C1C=Cc2c(-c3cccc4ccccc34)cccc21)C1C=Cc2c(-c3cccc4ccccc34)cccc21.[Cl-].[Cl-]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.31
SLC6A3 known ✓ Q01959 1/20 0.31
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32
ALOX15 P16050 1/20 0.32
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
CYP2D6 P10635 1/20 0.31
SLC6A4 P31645 1/20 0.31
KDM4E B2RXH2 3/20 0.31
ALDH1A1 P00352 3/20 0.31
MAPT P10636 3/20 0.31
HPGD P15428 3/20 0.31
MAPK1 P28482 3/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TP53 P04637 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7641939 0.94 KDM4E (0.34) HDAC8HDAC6SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL8164242 0.92
Hydrochloric Acid SCHEMBL7167465 0.88
Hydrochloric Acid SCHEMBL5177193 0.86 ALDH1A1 (0.34) MTNR1AMTNR1BKDM4EALDH1A1MAPT
Hydrochloric Acid SCHEMBL7644367 0.81 KDM1A (0.33) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
Hydrochloric Acid SCHEMBL7166643 0.81 KDM4E (0.30) KDM4EALDH1A1MAPTHPGD
Hydrochloric Acid SCHEMBL8163879 0.78
Hydrochloric Acid SCHEMBL7641960 0.77 KDM1A (0.30)
Hydrochloric Acid SCHEMBL7642682 0.76 PDCD1 (0.31) EDNRBEDNRA
Hydrochloric Acid SCHEMBL7640265 0.76 TNF (0.33) KDM4EALDH1A1MAPTHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6472490-B1 AN ETHYLENE-AROMATIC VINYL COMPOUND COPOLYMER HAVING AN AROMATIC VINYL COMPOUND CONTENT OF FROM 1 TO LESS THAN 55% BY MOLAR FRACTION, WHICH HAS A HAZE OF AT MOST 41.5% WHEN MOLDED; METHINE DYES DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-10-29 US disclosed
US-6348556-B1 COORDINATION CATALYST OF TRANSITION METAL COMPLEX CONTAINING INDENYL GROUP(S) AND COCATALYST; ISOTACTIC; CATALYSIS, ADDITION COPOLYMERIZATION DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-02-19 US disclosed
US-6066709-A Ethylene-aromatic vinyl compound copolymer and method for its production DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-05-23 US disclosed
US-5883213-A STEREOREGULARITY DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-03-16 US disclosed