Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7167465 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL7641939 | 0.86 | KDM4E (0.34) | KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL7159637 | 0.84 | CASP3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7163898 | 0.84 | HPGD (0.32) | KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL8163879 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL7644118 | 0.81 | MTNR1A (0.32) | KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL8164242 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL7642682 | 0.76 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5177193 | 0.76 | ALDH1A1 (0.34) | KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL7163950 | 0.75 | NPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559234-B1 | Firstly provides a novel olefin/styrene/ diene type cross-copolymer having excellent physical properties and mechanical properties, and a novel, efficient and economically excellent process for its production. It provides an efficient | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2003-05-06 | — | — | US | disclosed |