Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110468 | 0.86 | ALDH1A1 (0.41) | CYP3A4CYP2C9CYP2C19CA12CA1 | |
| SCHEMBL6493288 | 0.84 | POLB (0.39) | CYP3A4CYP2C9CYP2C19POLBCA12 | |
| SCHEMBL7103296 | 0.80 | LPAR3 (0.43) | TSHR | |
| SCHEMBL331957 | 0.79 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP2C19POLBGAA | |
| SCHEMBL9325074 | 0.76 | CYP3A4 (0.42) | CYP3A4CYP2C9CYP2C19POLBCA12 | |
| SCHEMBL5892273 | 0.74 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2C19POLBCA12 | |
| SCHEMBL6483365 | 0.74 | CYP3A4 (0.39) | CYP3A4CYP2C9CYP2C19POLBCA12 | |
| SCHEMBL12631725 | 0.74 | ALDH1A1 (0.34) | CYP3A4CYP2C9CYP2C19POLBGAA | |
| SCHEMBL9377677 | 0.73 | CYP3A4 (0.39) | CYP3A4CYP2C9CYP2C19POLBGAA | |
| SCHEMBL420551 | 0.72 | ALDH1A1 (0.38) | CYP3A4CYP2C9CYP2C19POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254101-A1 | PROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF DIABETES AND OBESITY | Novo Nordisk A/S (DK) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055085-A1 | PROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF DIABETES AND OBESITY | NOVO NORDISK A/S (DK) | 2001-08-02 | — | — | WO | disclosed |