Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103296 | 0.87 | LPAR3 (0.43) | TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL7644205 | 0.86 | CYP3A4 (0.35) | ALDH1A1CYP3A4TSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL6483365 | 0.85 | CYP3A4 (0.39) | ALDH1A1CYP3A4TSHRCYP2C19LPAR1 | |
| SCHEMBL14105290 | 0.79 | ALDH1A1 (0.44) | ALDH1A1ATMCYP3A4TSHRHPGD | |
| SCHEMBL6496046 | 0.79 | LPAR3 (0.44) | TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL331957 | 0.77 | CYP3A4 (0.38) | ALDH1A1CYP3A4TSHRLMNACYP2C19 | |
| SCHEMBL6493288 | 0.74 | POLB (0.39) | ALDH1A1CYP3A4TSHRLMNACYP2C19 | |
| SCHEMBL7106243 | 0.72 | POLB (0.43) | LMNASMN1; SMN2LPAR1MEN1KMT2A | |
| SCHEMBL10343805 | 0.72 | CYP3A4 (0.43) | CYP3A4TSHRHPGDCYP2C19SMN1; SMN2 | |
| SCHEMBL5892273 | 0.72 | CYP3A4 (0.40) | ALDH1A1CYP3A4TSHRCYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008361-A1 | Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids | EBDRUP SOREN (DK) | 2003-01-09 | — | — | US | disclosed |
| CN-1375013-A | Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids | NOVO NORDISK AS (DK) | 2002-10-16 | — | — | CN | disclosed |
| EP-1206565-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001011073-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2001-02-15 | — | — | WO | disclosed |