Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110468 | 0.87 | ALDH1A1 (0.41) | LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL6496046 | 0.86 | LPAR3 (0.44) | LPAR3LPAR1LPAR2LPAR5TSHR | |
| SCHEMBL331957 | 0.81 | CYP3A4 (0.38) | TSHR | |
| SCHEMBL7644205 | 0.80 | CYP3A4 (0.35) | TSHR | |
| SCHEMBL6483365 | 0.79 | CYP3A4 (0.39) | LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL7106243 | 0.78 | POLB (0.43) | LPAR1 | |
| SCHEMBL9377677 | 0.76 | CYP3A4 (0.39) | TSHR | |
| SCHEMBL12631725 | 0.76 | ALDH1A1 (0.34) | TSHR | |
| SCHEMBL420551 | 0.74 | ALDH1A1 (0.38) | TSHR | |
| SCHEMBL3674519 | 0.74 | SMPD1 (0.42) | LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008361-A1 | Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids | EBDRUP SOREN (DK) | 2003-01-09 | — | — | US | disclosed |
| CN-1375013-A | Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids | NOVO NORDISK AS (DK) | 2002-10-16 | — | — | CN | disclosed |
| EP-1206565-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001011073-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2001-02-15 | — | — | WO | disclosed |