SCHEMBL7644206

SCHEMBL7644206

COc1cc(N)ccc1C(=O)CCC1CCN(CCNS(C)(=O)=O)CC1

nearest known ligand 0.74

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 3/20 0.74
MEN1 O00255 2/20 0.74
ALDH1A1 P00352 2/20 0.74
CYP3A4 P08684 2/20 0.74
CYP2D6 P10635 2/20 0.74
CYP2C19 P33261 2/20 0.74
KMT2A Q03164 2/20 0.74
CYP2C9 P11712 1/20 0.74
ACHE P22303 2/20 0.71
HTR6 P50406 5/20 0.61
TP53 P04637 1/20 0.59
HTR2A P28223 1/20 0.58
HTR2C P28335 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548884 0.85 HTR4 (1.00) HTR4MEN1ALDH1A1CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL1078401 0.84 HTR4 (0.98) HTR4MEN1ALDH1A1CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL678966 0.84 HTR4 (0.96) HTR4MEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL17709619 0.83 HTR4 (1.00) HTR4MEN1ALDH1A1CYP2D6KMT2A
SCHEMBL7644209 0.81 HTR4 (0.60) HTR4MEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL7358666 0.80 HTR4 (0.90) HTR4MEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL17709633 0.80 MEN1 (0.72) HTR4MEN1ALDH1A1CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL7362378 0.79 HTR4 (0.88) HTR4MEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL17709650 0.79 ACHE (1.00) HTR4ACHE
SCHEMBL16403712 0.79 HTR4 (0.70) HTR4MEN1ALDH1A1CYP2D6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020039599-A1 Calibration; administering antiseptic compound NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-04-04 US disclosed