Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | HTR6 | P50406 | 5/20 | 0.79 |
| ▸ | HTR2A | P28223 | 1/20 | 0.75 |
| ▸ | HTR2C | P28335 | 1/20 | 0.75 |
| ▸ | ACHE | P22303 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1078401 | 0.99 | HTR4 (0.98) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL678966 | 0.98 | HTR4 (0.96) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL7358666 | 0.95 | HTR4 (0.90) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL7362378 | 0.94 | HTR4 (0.88) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL7357278 | 0.90 | HTR4 (0.82) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL7351744 | 0.90 | HTR4 (0.81) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL7360018 | 0.90 | HTR4 (0.81) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL2946020 | 0.89 | MEN1 (1.00) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL2946335 | 0.88 | MEN1 (0.98) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL7354179 | 0.88 | HTR4 (0.78) | HTR4MEN1ALDH1A1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11571397-B2 | Compositions and methods for treating seizure-induced sudden death | ZOGENIX INTERNATIONAL LIMITED (GB) | 2023-02-07 | — | — | US | claimed |
| US-20220273680-A1 | Methods of Treating Psychological and Brain Disorders | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2022-09-01 | — | — | US | claimed |
| CN-114599355-A | Method for treating psychological and cerebral diseases | 马里兰大学巴尔的摩分校 | 2022-06-07 | — | — | CN | claimed |
| US-8388935-B2 | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions | CEDARS-SINAI MEDICAL CENTER (US) | 2013-03-05 | — | — | US | claimed |
| US-20120263790-A1 | METHODS OF DIAGNOSING AND TREATING SMALL INTESTINAL BACTERIAL OVERGROWTH (SIBO) AND SIBO-RELATED CONDITIONS | CEDARS-SINAI MEDICAL CENTER (US) | 2012-10-18 | — | — | US | claimed |
| US-20090170899-A1 | Stimulators of 5-HT4 receptors and uses thereof | MCGILL UNIVERSITY (CA) | 2009-07-02 | — | — | US | claimed |
| WO-2006029520-A1 | STIMULATORS OF 5-HT4 RECEPTORS AND USES THEREOF | MCGILL UNIVERSITY (CA) | 2006-03-23 | — | — | WO | claimed |
| EP-4706758-A2 | METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-4076499-B1 | USE OF GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR (GDNF) FOR THE TREATMENT OF ENTERIC NEUROPATHIES | TRANSFERT PLUS SOC EN COMMANDITE (CA) | 2025-07-16 | — | — | EP | disclosed |
| US-20250213564-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER NEUROGENERATIVE DISEASE | THE RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. | 2025-07-03 | — | — | US | disclosed |
| EP-4577305-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER NEUROGENERATIVE DISEASE | 1/1THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-07-02 | — | — | EP | disclosed |
| US-20240325487-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2024-10-03 | — | — | US | disclosed |
| US-20240100018-A1 | COMPOUNDS FOR THE TREATMENT OF A DISEASE OR DISORDER, METHODS FOR IDENTIFYING SAID COMPOUNDS | CEDARS-SINAI MEDICAL CENTER | 2024-03-28 | — | — | US | disclosed |
| WO-2005004865-A1 | USE OF 5-HT4(A)-SEROTONIN RECEPTOR AGONISTS | GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN (DE) | 2005-01-20 | — | — | WO | disclosed |
| WO-2004105795-A1 | PHARMACEUTICAL COMBINATIONS OF A PROTON PUMP INHIBITOR AND A COMPOUND WHICH MODIFIES GASTROINTESTINAL MOTILITY | ALTANA PHARMA AG (DE) | 2004-12-09 | — | — | WO | disclosed |
| EP-1385476-A2 | METHODS OF DIAGNOSING AND TREATING SMALL INTESTINAL BACTERIAL OVERGROWTH (SIBO) AND SIBO-RELATED CONDITIONS | CEDARS-SINAI MEDICAL CENTER (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083926-A2 | METHODS OF DIAGNOSING AND TREATING SMALL INTESTINAL BACTERIAL OVERGROWTH (SIBO) AND SIBO-RELATED CONDITIONS | CEDARS-SINAI MEDICAL CENTER (US) | 2002-10-24 | — | — | WO | disclosed |
| EP-0700383-B1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX INC (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5763458-A | NERVOUS SYSTEM DISORDERS, ANXIETY, ANTIDEPRESSANTS AND COGNITION ACTIVATORS | SYNTEX (U.S.A.) INC. (US) | 1998-06-09 | — | — | US | disclosed |
| WO-1994027965-A1 | NOVEL 1-PHENYLALKANONE 5-HT4 RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240325487-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC34A3, SLC34A2, SLC34A1 | HTR4 1928/4885MEN1 2203/4885ALDH1A1 4094/4885 |
| US-11571397-B2 | Compositions and methods for treating seizure-induced sudden death | HTR4, HTR5A, HTR1A | HTR4 1/4885MEN1 2202/4885ALDH1A1 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.