SCHEMBL7644284

SCHEMBL7644284

CC=CC=CC(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.33
F2 P00734 1/20 0.33
TSHR P16473 1/20 0.33
GABBR2 O75899 1/20 0.33
GABBR1 Q9UBS5 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
TAAR1 Q96RJ0 2/20 0.32
LMNA P02545 2/20 0.32
HTR2A P28223 1/20 0.32
HRH1 P35367 1/20 0.32
CYP3A4 P08684 1/20 0.32
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2C P18825 1/20 0.31
CYP2D6 P10635 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27578731 0.84 DPP4 (0.35) DPP4F2TSHRTAAR1LMNA
SCHEMBL8613849 0.83 MEN1 (0.39) DPP4F2TSHRMEN1KMT2A
SCHEMBL692130 0.83 MEN1 (0.39) DPP4F2TSHRMEN1KMT2A
Methane SCHEMBL11662057 0.81 MEN1 (0.38) DPP4F2TSHRMEN1KMT2A
SCHEMBL28366839 0.80 TRPA1 (0.41) TAAR1LMNAKDM4EADRA2AADRA2C
SCHEMBL8522965 0.77 DPP4 (0.45) DPP4F2TSHRTAAR1LMNA
SCHEMBL15271338 0.74 ALDH1A1 (0.44) DPP4F2TSHRKMT2ALMNA
SCHEMBL30534983 0.74 KDM4E (0.39) DPP4F2TSHRMEN1KMT2A
Water SCHEMBL27614773 0.74 CYP3A4 (0.36) DPP4F2TSHRMEN1KMT2A
Hydrochloric Acid SCHEMBL11729507 0.73 GABBR2 (0.33) GABBR2GABBR1CYP3A4HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1230279-A2 DELAYED ACTIVITY SUPPORTED OLEFIN POLYMERIZATION CATALYST COMPOSITIONS AND METHOD FOR MAKING AND USING THE SAME BP Chemicals Limited (GB) 2002-08-14 EP disclosed
WO-2000063262-A2 DELAYED ACTIVITY SUPPORTED OLEFIN POLYMERIZATION CATALYST COMPOSITIONS AND METHOD FOR MAKING AND USING THE SAME BP CHEMICALS LIMITED (GB) 2000-10-26 WO disclosed