SCHEMBL7644388

SCHEMBL7644388

CCCCCCCCC(OC(=O)OC(CCCCCCCC)c1ccccc1C(=O)OCC)c1ccccc1C(=O)OCC

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
PRSS3 P35030 1/20 0.52
ALDH1A1 P00352 7/20 0.50
TSHR P16473 5/20 0.50
LMNA P02545 2/20 0.50
CYP3A4 P08684 2/20 0.48
TP53 P04637 1/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HSD17B10 Q99714 4/20 0.45
KDM4E B2RXH2 3/20 0.45
CA2 P00918 1/20 0.45
POLB P06746 1/20 0.45
SLC37A4 O43826 1/20 0.40
CDC25A P30304 1/20 0.40
CDC25B P30305 1/20 0.40
CDC25C P30307 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7036470 1.00 PRSS1 (0.52) PRSS1PRSS2PRSS3ALDH1A1TSHR
SCHEMBL6467391 0.95 TSHR (0.53) PRSS1PRSS2PRSS3ALDH1A1TSHR
SCHEMBL7036476 0.91 PRSS1 (0.51) PRSS1PRSS2PRSS3ALDH1A1TSHR
SCHEMBL7643422 0.88 ALDH1A1 (0.49) PRSS1PRSS2PRSS3ALDH1A1TSHR
SCHEMBL7200254 0.88 ALDH1A1 (0.49) PRSS1PRSS2PRSS3ALDH1A1TSHR
SCHEMBL6436469 0.88 ALDH1A1 (0.49) PRSS1PRSS2PRSS3ALDH1A1TSHR
SCHEMBL7643004 0.87 ALDH1A1 (0.47) PRSS1PRSS2PRSS3ALDH1A1TSHR
SCHEMBL6467404 0.86 TSHR (0.51) PRSS1PRSS2PRSS3ALDH1A1TSHR
SCHEMBL6472205 0.83 CYP1A2 (0.45) PRSS1PRSS2PRSS3ALDH1A1TSHR
SCHEMBL9065461 0.80 ALDH1A1 (0.57) PRSS1PRSS2PRSS3ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410777-B1 HALOGEN-FREE TEIJIN LIMITED (JP) 2002-06-25 US disclosed
EP-0980861-A1 SALICYLIC ESTER DERIVATIVES AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 2000-02-23 EP disclosed