Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200254 | 1.00 | ALDH1A1 (0.49) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL7643422 | 1.00 | ALDH1A1 (0.49) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL7643004 | 0.99 | ALDH1A1 (0.47) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL6472205 | 0.95 | CYP1A2 (0.45) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL6436479 | 0.91 | ALDH1A1 (0.51) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL7639705 | 0.89 | LMNA (0.44) | ALDH1A1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7036470 | 0.88 | PRSS1 (0.52) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL7644388 | 0.88 | PRSS1 (0.52) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL6472214 | 0.85 | ALDH1A1 (0.44) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL2655007 | 0.83 | PPARG (0.56) | ALDH1A1PRSS1PRSS2PRSS3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1191064-B1 | AROMATIC POLYCARBONATE COMPOSITION | TEIJIN LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6448365-B1 | Aromatic polycarbonate composition | TEIJIN LIMITED (JP) | 2002-09-10 | — | — | US | disclosed |
| EP-1191064-A1 | AROMATIC POLYCARBONATE COMPOSITION | TEIJIN LIMITED (JP) | 2002-03-27 | — | — | EP | disclosed |