SCHEMBL6472205

SCHEMBL6472205

CCCCC(OC(=O)OC(CCCC)c1ccccc1C(=O)OC)c1ccccc1C(=O)OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 5/20 0.45
CYP3A4 P08684 2/20 0.45
CA2 P00918 1/20 0.45
TSHR P16473 6/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 3/20 0.41
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 2/20 0.41
ALOX12 P18054 1/20 0.41
HSD17B10 Q99714 2/20 0.41
CFTR P13569 1/20 0.41
KDM4E B2RXH2 2/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7643004 0.96 ALDH1A1 (0.47) CYP1A2CYP2C19SMN1; SMN2ALDH1A1CYP3A4
SCHEMBL6436469 0.95 ALDH1A1 (0.49) CYP1A2CYP2C19SMN1; SMN2ALDH1A1CYP3A4
SCHEMBL7643422 0.95 ALDH1A1 (0.49) CYP1A2CYP2C19SMN1; SMN2ALDH1A1CYP3A4
SCHEMBL7200254 0.95 ALDH1A1 (0.49) CYP1A2CYP2C19SMN1; SMN2ALDH1A1CYP3A4
SCHEMBL7639705 0.92 LMNA (0.44) CYP1A2CYP2C19SMN1; SMN2ALDH1A1CA2
SCHEMBL6472214 0.90 ALDH1A1 (0.44) CYP1A2CYP2C19SMN1; SMN2ALDH1A1CYP3A4
SCHEMBL6467391 0.88 TSHR (0.53) ALDH1A1CYP3A4CA2TSHRTDP1
SCHEMBL6436479 0.85 ALDH1A1 (0.51) CYP1A2CYP2C19SMN1; SMN2ALDH1A1CYP3A4
SCHEMBL7036470 0.83 PRSS1 (0.52) ALDH1A1CYP3A4CA2TSHRTDP1
SCHEMBL7644388 0.83 PRSS1 (0.52) ALDH1A1CYP3A4CA2TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1191064-B1 AROMATIC POLYCARBONATE COMPOSITION TEIJIN LTD (JP) 2005-12-07 EP disclosed
US-20030195329-A1 Aromatic polycarbonate, composition thereof , and use TEIJIN LIMITED (JP) 2003-10-16 US disclosed
US-6608165-B2 Melt polycondensing a dihydroxy compound and a carbonic acid diester in the presence of an ester exchange catalyst TEIJIN LIMITED (JP) 2003-08-19 US disclosed
US-20030060593-A1 Aromatic polycarbonate and process for their production TEIJIN LIMITED (JP) 2003-03-27 US disclosed
EP-1275694-A1 AROMATIC POLYCARBONATE COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2003-01-15 EP disclosed
US-6448365-B1 Aromatic polycarbonate composition TEIJIN LIMITED (JP) 2002-09-10 US disclosed
US-20020103328-A1 Aromatic polycarbonate composition, production process therefor and molded product thereof TEIJIN LIMITED 2002-08-01 US disclosed
EP-1191064-A1 AROMATIC POLYCARBONATE COMPOSITION TEIJIN LIMITED (JP) 2002-03-27 EP disclosed