Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL395682 | 0.90 | HTR2A (0.39) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL29574289 | 0.90 | HTR2A (0.39) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL3670932 | 0.88 | HTR2A (0.38) | HTR6HTR2ASIGMAR1 | |
| Ethylene SCHEMBL4978169 | 0.86 | HTR2A (0.36) | HTR6HTR2ASIGMAR1 | |
| Bromide SCHEMBL5368508 | 0.86 | HTR2A (0.43) | HTR6HTR2ASIGMAR1 | |
| Fluoride Ion SCHEMBL7637223 | 0.86 | HTR2A (0.39) | HTR6HTR2ASIGMAR1 | |
| SCHEMBL4576586 | 0.86 | HTR2A (0.39) | HTR6HTR2ASIGMAR1 | |
| Bromide SCHEMBL31427621 | 0.86 | HTR2A (0.43) | HTR6HTR2ASIGMAR1 | |
| SCHEMBL7032645 | 0.82 | HTR2A (0.36) | HTR6HTR2ASIGMAR1 | |
| Phenol SCHEMBL7826917 | 0.81 | HTR6 (0.37) | HTR6HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395846-B1 | COORDINATION CATALYST COMPRISING CLAY, ORGANOSILANE COMPOUND, WATER, AND TRANSITION METAL COMPLEX; QUALITY | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| US-6255244-B1 | OBTAINED BY CONTACTING A TRANSITION METAL COMPOUND, AN OXYGEN-CONTAINING COMPOUND TO FORM AN IONIC COMPLEX, AND AN ADSORBING SUBSTANCE DURING OR AFTER THE CONTACTING TREATMENT, THEN FOLLOWED BY REMOVING THE ADSORBING SUBSTANCE. | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-1026176-A1 | CATALYST FOR OLEFIN POLYMER PRODUCTION, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING OLEFIN POLYMER | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2000-08-09 | — | — | EP | disclosed |