Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL764475 | 0.88 | P2RX7 (0.40) | SCDBDKRB1SCN3APOLBALDH1A1 | |
| SCHEMBL764440 | 0.85 | SCD (0.37) | SCDBDKRB1SCN3A | |
| SCHEMBL10121269 | 0.81 | BDKRB1 (0.56) | SCDBDKRB1MAPK14LPAR1LPAR5 | |
| SCHEMBL12238933 | 0.75 | P2RX7 (0.44) | BDKRB1POLBALDH1A1 | |
| SCHEMBL12238931 | 0.73 | EPHX2 (0.53) | BDKRB1MAPK14 | |
| SCHEMBL765545 | 0.73 | DDR2 (0.44) | BDKRB1MAPK14PTGS2 | |
| SCHEMBL765827 | 0.73 | BDKRB1 (0.39) | BDKRB1MAPK14ALDH1A1HPGD | |
| SCHEMBL13191708 | 0.73 | BDKRB1 (0.48) | SCDBDKRB1LPAR1LPAR5 | |
| SCHEMBL756608 | 0.72 | LMNA (0.47) | BDKRB1POLBHPGD | |
| SCHEMBL12262769 | 0.72 | BDKRB1 (0.58) | BDKRB1MAPK14HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |