Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637178 | 0.94 | CYP19A1 (0.43) | CYP19A1ALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL7644928 | 0.84 | HDAC1 (0.33) | CYP19A1TSHR | |
| SCHEMBL7641429 | 0.78 | IDH1 (0.37) | CYP19A1ALDH1A1MAPTKDM4E | |
| SCHEMBL7641485 | 0.78 | HDAC1 (0.33) | CYP19A1TSHR | |
| SCHEMBL3265800 | 0.77 | CYP1A2 (0.45) | KDM4E | |
| SCHEMBL7634148 | 0.77 | SMN1; SMN2 (0.33) | ALDH1A1MAPTTSHRGAATP53 | |
| SCHEMBL7645535 | 0.76 | CYP3A4 (0.48) | CYP19A1ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL3927363 | 0.76 | TK1 (0.47) | — | |
| SCHEMBL7637994 | 0.74 | RNF4 (0.41) | ALDH1A1MAPTL3MBTL1TP53NPSR1 | |
| SCHEMBL3249567 | 0.72 | RET (0.47) | ALDH1A1MAPTTP53KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7258222-A | — | — | None | — | — | JP | disclosed |
| US-6465650-B1 | INTERMEDIATE STEPS IN PREPARING PEPTIDE NUCLEIC ACIDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-10-15 | — | — | US | disclosed |
| US-6075143-A | USEFUL FOR FORMING PEPTIDE NUCLEIC ACIDS OR HYBRID OF PEPTIDE NUCLEIC ACIDS AND DEOXYNUCLEIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
| JP-H07258222-A | SUBSTITUTED N-ETHYLGLYCINE DERIVATIVE FOR PRODUCING PNA AND PNA/DNA HYBRID | HOECHST AG | 1995-10-09 | — | — | JP | disclosed |