Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.50 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.50 |
| ▸ | OPRD1 known ✓ | P41143 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207554 | 0.85 | ALDH1A1 (0.62) | ALDH1A1POLBHPGDCYP3A4HSD17B10 | |
| SCHEMBL29374052 | 0.85 | ALDH1A1 (0.62) | ALDH1A1POLBHPGDCYP3A4HSD17B10 | |
| SCHEMBL29655855 | 0.84 | ALDH1A1 (0.62) | ALDH1A1POLBHPGDCYP3A4HSD17B10 | |
| SCHEMBL1508924 | 0.84 | ALDH1A1 (0.62) | ALDH1A1POLBHPGDCYP3A4HSD17B10 | |
| SCHEMBL7645545 | 0.82 | ALDH1A1 (0.60) | ALDH1A1POLBHPGDCYP3A4HSD17B10 | |
| SCHEMBL24660121 | 0.79 | ALDH1A1 (0.52) | ALDH1A1POLBHPGDCYP3A4HSD17B10 | |
| SCHEMBL484005 | 0.79 | CYP3A4 (0.52) | ALDH1A1POLBHPGDCYP3A4HSD17B10 | |
| SCHEMBL11117613 | 0.78 | ALDH1A1 (0.66) | ALDH1A1POLBHPGDCYP3A4HSD17B10 | |
| SCHEMBL6114392 | 0.77 | ALDH1A1 (0.50) | ALDH1A1POLBHPGDCYP3A4HSD17B10 | |
| Bitoscanate SCHEMBL8443297 | 0.76 | CA1 (0.63) | ALDH1A1POLBHPGDCYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994509-A | Method for obtaining uniform fractions of hyperpolymeric hemoglobins | SANGUIBIOTECH AG (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0855392-A2 | Five-membered heterocycles having biphenylsulphonyl substituents, processes for the preparation thereof, their use as medicaments or diagnostic agent and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-29 | — | — | EP | disclosed |
| EP-0854151-A1 | Process for the preparation of uniform fractions of hyperpolymers of haemoglobin | SanguiBioTech AG (DE) | 1998-07-22 | — | — | EP | disclosed |