Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790487 | 0.79 | MPI (0.44) | MPIMRGPRX4CCR1KMT2AMAPT | |
| SCHEMBL7645206 | 0.78 | PRSS1 (0.43) | KMT2AMAPTMEN1GAA | |
| SCHEMBL7648084 | 0.77 | MEN1 (0.45) | KMT2AMAPTMEN1HTTLMNA | |
| SCHEMBL11935561 | 0.74 | FERMT2 (0.55) | MPICCR1KMT2AMAPTMEN1 | |
| SCHEMBL7646146 | 0.74 | ABL1 (0.43) | KMT2AMAPTMEN1HTTPKM | |
| SCHEMBL10396655 | 0.73 | LMNA (0.46) | MRGPRX4KMT2AMAPTMEN1HTT | |
| SCHEMBL7646267 | 0.73 | ABL1 (0.33) | — | |
| SCHEMBL7645784 | 0.72 | CA1 (0.48) | MPIMRGPRX4KMT2AMAPTMEN1 | |
| SCHEMBL17513470 | 0.71 | TDP1 (0.54) | MPIMRGPRX4KMT2AMAPTMEN1 | |
| SCHEMBL14140880 | 0.70 | MRGPRX4 (0.47) | MPIMRGPRX4KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | claimed |