Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.31 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646146 | 0.84 | ABL1 (0.43) | ABL1 | |
| SCHEMBL7650972 | 0.78 | THRB (0.43) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7645206 | 0.78 | PRSS1 (0.43) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7648084 | 0.78 | MEN1 (0.45) | — | |
| SCHEMBL7646888 | 0.74 | ALDH1A1 (0.57) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7645786 | 0.73 | MPI (0.43) | — | |
| SCHEMBL7648479 | 0.71 | MAPT (0.53) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7650078 | 0.71 | ALDH1A1 (0.64) | PRSS1 | |
| SCHEMBL7646266 | 0.69 | S1PR1 (0.37) | ABL1 | |
| SCHEMBL7647293 | 0.68 | GAA (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | disclosed |