Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645193 | 0.89 | CA1 (0.39) | CA1CA14MPILMNAGGPS1 | |
| SCHEMBL7645204 | 0.78 | RHOC (0.45) | CA14LMNASMN1; SMN2GAAMEN1 | |
| SCHEMBL7648081 | 0.77 | EPHX1 (0.44) | LMNASMN1; SMN2HPGDL3MBTL1GAA | |
| SCHEMBL7646938 | 0.75 | RHOC (0.41) | LMNAL3MBTL1GAAMEN1MAPT | |
| SCHEMBL7646145 | 0.75 | MMP8 (0.46) | CA14SMN1; SMN2L3MBTL1MEN1MAPT | |
| SCHEMBL7790487 | 0.74 | MPI (0.44) | MPILMNASMN1; SMN2MRGPRX4HPGD | |
| SCHEMBL7646266 | 0.74 | S1PR1 (0.37) | CA14LMNAL3MBTL1THRBGAA | |
| SCHEMBL10396655 | 0.72 | LMNA (0.46) | CA1CA14LMNASMN1; SMN2MRGPRX4 | |
| SCHEMBL7531364 | 0.72 | LMNA (0.58) | CA1CA14LMNASMN1; SMN2MRGPRX4 | |
| SCHEMBL7645786 | 0.72 | MPI (0.43) | CA1CA14MPILMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | claimed |